Skeletal Lead Burden in Aborigine Petrol Sniffers

Eastwell, Harry D.; Thomas, Brian; Thomas, B. W.

doi:10.1016/s0140-6736(83)90561-5

Cited by 18 publications

(6 citation statements)

References 5 publications

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“…Recently, however, the need to monitor the accumulating body burden of absorbed lead in industrial workers has resulted in the development of an X-ray fluorescence method of estimating bone lead content in living persons (Christoffersson et al 1984, Ahlgren ct al. 1980, Eastwell et al 1983).…”

Section: Lead Concentration (Measured In Bone and Derivedfor Blood) mentioning

confidence: 99%

Patterning of Skeletal Lead Content in Barbados Slaves

et al. 1987

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Skeletal lead levels are unexpectedly high (averaging 118 ppm and reaching 424 ppm maximum) in seventeenth to nineteenth century Caribbean slave skull remains. Younger specimens show significantly lower lead concentrations. Historical data confirm the supposition from skeletal lead measurements that blood lead levels probably resulted in lead intoxication symptoms in a significant fraction of this population.

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Section: Lead Concentration (Measured In Bone and Derivedfor Blood) mentioning

confidence: 99%

Patterning of Skeletal Lead Content in Barbados Slaves

et al. 1987

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“…Since modern medical experience demonstrates a rough but useful correlation between blood lead concentration and at least certain lead poisoning symptoms (Hernberg,198o), it becomes possible to predict symptoms of lead toxicity that would have been expected in Newton's living slave population. The x-ray fluorescent method provides a small but useful body of relevant data (Ahlgren et al, 1980;Christoffersson et al, 1984;Eastwell et al, 1983;Scott, 1985). Through regression analysis of such data, using the individual's age (ascertained from the skeletal remains) as the years of lead exposure, the mean blood lead level for each Newton slave was estimated from the measured bone lead concentration.…”

Section: Clinical Implications Of Skeletal Lead Contentmentioning

confidence: 99%

Lead Contact and Poisoning in Barbados Slaves: Historical, Chemical, and Biological Evidence

Handler¹,

Aufderheide²,

Corruccini³

et al. 1986

Social Science History

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Lead contact and lead poisoning have received scant attention in discussions of early West Indian societies but are potentially important issues in considering the health and medical problems of blacks. Although our discussion focuses on Barbados, the West Indian historical literature strongly suggests that our general findings are applicable to other Caribbean areas and have implications for understanding some of the disabilities of early white populations as well. In this paper we also seek to illustrate how bioanthropological and chemical analyses of slave skeletal remains and historical data can complement one another in defining and investigating various dimensions of slave life.

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“…3 The diagnosis is easily made if a history of petrol sniffing is available but the clinical signs and symptoms vary to some extent depending upon the chronicity of the intoxication. Most patients respond well to the detoxification and chelation regimens and hence there are very few clinicopathological studies of such cases.…”

mentioning

confidence: 99%

“…A severe encephalopathy resulting from repeated sniffing of leaded petrol has been reported in individual case reports' and as an almost endemic phenomenon in certain areas of Northern Canada 1 and Australia. 3 The diagnosis is easily made if a history of petrol sniffing is available but the clinical signs and symptoms vary to some extent depending upon the chronicity of the intoxication. Most patients respond well to the detoxification and chelation regimens and hence there are very few clinicopathological studies of such cases.…”

mentioning

confidence: 99%

Acute Encephalopathy and Death Due to Petrol Sniffing: Neuropathological Findings

Kaelan¹,

Harper

Vieira³

1986

Australian and New Zealand Journal of Medicine

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A 25 year old man with a five year history of petrol sniffing developed an acute encephalopathy with abnormal body movements and died of aspiration pneumonia. Neuropathological findings included chromatolysis of neurons in the reticular formation and cerebral cortex and loss of neurons in the h3-5 sector of Ammon's horn and the cerebellum. Toxicological studies suggest that the encephalopathy is caused by the tetraethyl-lead additive in the petrol. These data support previous human and experimental studies.

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Skeletal Lead Burden in Aborigine Petrol Sniffers

Cited by 18 publications

References 5 publications

Patterning of Skeletal Lead Content in Barbados Slaves

Patterning of Skeletal Lead Content in Barbados Slaves

Lead Contact and Poisoning in Barbados Slaves: Historical, Chemical, and Biological Evidence

Acute Encephalopathy and Death Due to Petrol Sniffing: Neuropathological Findings

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