Skeletal muscle metastases as the initial manifestation of an unknown primary lung cancer detected on F-18 fluorodeoxyglucose positron emission tomography/computed tomography

Agrawal, Kanhaiyalal; Bhattacharya, Anish; Singh, Navneet; Harisankar, Chidambaram Natarajan Balasubramanian; Mittal, Bhagwant Rai

doi:10.4103/0972-3919.116814

Cited by 5 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An isolated, painful skeletal muscle metastasis as the initial manifestation of an otherwise asymptomatic primary malignancy, as in our patient, is uncommon [ 6 , 9 , 14 ]. Muscular metastases typically present as a painful and frequently palpable mass with or without localized swelling [ 2 ].…”

Section: Discussionmentioning

confidence: 98%

“…A subgroup analysis revealed that masses of pulmonary origin had low central attenuation with rim enhancement as the most common finding on CT [ 13 ]. Correlation with FDG-PET is recommended in all patients with a history of malignancy or a suspicion lesion [ 3 , 8 , 9 , 18 ]. Biopsy of these masses is mandatory for proper diagnosis and further management [ 6 , 9 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pulmonary Adenocarcinoma Presenting as Paraspinal Muscle Metastatic Mass

Harrison

Jones

Abebe

2018

Case Reports in Oncological Medicine

View full text Add to dashboard Cite

A 39-year-old male presented with a painful paraspinal mass, which had been present for several weeks. The mass had previously been treated with oral sulfamethoxazole and trimethoprim DS, as the patient reported a history of “boils,” with no improvement in his pain or size of the mass. No further diagnostic workup was pursued until he was admitted with intractable pain. Eventual biopsy revealed adenocarcinoma, likely of pulmonary origin. This report, as well as other incoming cases, highlights this rare phenomenon of muscular metastases as the sole presentation of a distant primary malignancy.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Pulmonary Adenocarcinoma Presenting as Paraspinal Muscle Metastatic Mass

Harrison

Jones

Abebe

2018

Case Reports in Oncological Medicine

View full text Add to dashboard Cite

show abstract

“…The most common sites of skeletal muscle metastasis of lung cancer are the thigh, iliopsoas, and paraspinous muscles. Lesions have also been reported in the orbit and pectoral muscles [7][8][9][10]. Besides, some literature also reports the calf muscles being among the common spreading sites [11].…”

Section: Discussionmentioning

confidence: 99%

An Unusual Case of Lung Adenocarcinoma Metastasis to the Tricep Muscle: Four Years Disease-Free After Surgical Resection and Radiotherapy

Weeraddana¹,

Walgamage²,

Elkabbani³

et al. 2023

Cureus

View full text Add to dashboard Cite

Lung cancer is one of the leading causes of cancer-related death worldwide. Lung cancer commonly metastasizes to the liver, bone, and brain, but metastasis to skeletal muscles is rare. The development of metastasis in skeletal muscles indicates stage IV disease with a poor prognosis. The most effective treatment strategy is unclear. Palliative radiotherapy is often used to treat skeletal muscle metastases, and patient survival is poor, with an average survival of one year. Here we discuss the case of a 76-year-old female diagnosed with lung adenocarcinoma with metastasis to the trapezius muscle. Initially, she was treated with stereotactic body radiotherapy for stage T1 lung adenocarcinoma. Her follow-up surveillance positron emission tomography (PET) scan in 11 months showed an abnormal focal area of increased activity localizing to the long head of the right triceps muscle. The diagnosis was confirmed with an ultrasound-guided biopsy of the trapezius muscle. Following that, the patient underwent wedge resection of the right middle and upper lobe of the lung and partial right trapezius resection. Afterward, she was given radiation therapy at the tricep resection site. She remained disease-free for four years after excision and radiation therapy.

show abstract

“…Although rare, metastasis to skeletal muscles is well documented in nonsmall cell lung cancer (NSCLC). [ 1 2 ] Further, skeletal muscle metastasis (SMM) reflects and aggressive disease and patients with multiple muscle metastases have bad overall survival rates as compared to solitary muscle metastasis. [ 3 ] Lung carcinoma is a common cause of cardiac metastasis.…”

Section: Discussionmentioning

confidence: 99%

Disseminated skeletal muscle and cardiac metastasis from squamous cell carcinoma of the lung detected with FDG and FLT PET/CT

et al. 2016

Self Cite

View full text Add to dashboard Cite

Lung cancer is one of the leading cancers all over the world. Positron emission tomography (PET) using 18F fluorodeoxyglucose (18F FDG) is useful for staging of the disease and decide the appropriate management. 3’-deoxy-3’-18 F-fluorothymidine (18F FLT) is a tracer being extensively evaluated currently and is said to represent tumor proliferation. Common sites of metastases from lung cancer include adrenal glands, bone, and brain. Muscle metastasis and cardiac metastasis are uncommon findings. We report a case of squamous cell carcinoma of the lung with metastases to multiple skeletal muscles and myocardium detected with both FDG and FLT PET/computed tomography (CT).

show abstract

Skeletal muscle metastases as the initial manifestation of an unknown primary lung cancer detected on F-18 fluorodeoxyglucose positron emission tomography/computed tomography

Cited by 5 publications

References 6 publications

Pulmonary Adenocarcinoma Presenting as Paraspinal Muscle Metastatic Mass

Pulmonary Adenocarcinoma Presenting as Paraspinal Muscle Metastatic Mass

An Unusual Case of Lung Adenocarcinoma Metastasis to the Tricep Muscle: Four Years Disease-Free After Surgical Resection and Radiotherapy

Disseminated skeletal muscle and cardiac metastasis from squamous cell carcinoma of the lung detected with FDG and FLT PET/CT

Contact Info

Product

Resources

About