Skeletal Muscle Metastases in a Patient With Neuroendocrine Tumor

Santos-Cabalona, Wilhelmina delos; Kozyreva, Olga; Davidoff, Ashley; Wolfe, Gail; Hackford, Alan W.

doi:10.4021/wjon609w

Cited by 1 publication

(3 citation statements)

References 13 publications

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“…Multiple case reports have similarly characterized NET metastases to various intramuscular locations; however, in each of those cases a primary NET was identified. The site of metastasis in these cases was most commonly to the lower extremities and the primary tumor location was most frequently identified in the ileocecal region 28,29 . A few cases have been reported with unusual presumed primary NET locations, including the breast and the femoral sheath 6,30 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…The site of metastasis in these cases was most commonly to the lower extremities and the primary tumor location was most frequently identified in the ileocecal region. 28,29 A few cases have been reported with unusual presumed primary NET locations, including the breast and the femoral sheath. 6,30 The combination of preoperative imaging with PET Dotatate and exploratory surgery has dramatically improved identification of the primary NET tumor location.…”

Section: Discussionmentioning

confidence: 99%

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An abdominal wall neuroendocrine tumor of unknown primary origin: A case report and review of the literature

Jagiella-Lodise

Jagiella²,

Weitman

2022

Cancer Reports

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Background Neuroendocrine tumors (NETs) are neoplasms that arise from cells of the endocrine and nervous system. NETs, often found in the gastrointestinal tract, can be found anywhere in the body, and have metastatic potential. NETs occasionally present with metastatic disease without an identifiable primary tumor. Case A 79‐year‐old female patient presented with an abdominal wall mass. Percutaneous biopsy was consistent with a NET. Preoperative endoscopy and PillCam were unremarkable. PET Dotatate demonstrated uptake in the abdominal wall as well as vague uptake in the pelvis. Intraoperatively, we identified a suspicious nodule on the sigmoid colon, which was consistent with a drop metastasis on final pathology. Conclusion In this case report we present a patient with a NET metastasis to the abdominal wall without a known primary site. This case highlights the limitations of endoscopy and imaging in the workup of metastatic NETs. Additionally, this is a novel case report of a metastatic NET to the abdominal wall without an identifiable primary site.

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Section: Discussionmentioning

confidence: 99%