Skeletal muscle tuberculosis simultaneously involving multiple sites

Neogi, Devdatta Suhas; Bandekar, Shivanand; Chawla, Lokesh

doi:10.1097/bpb.0b013e328354b04d

Cited by 11 publications

(8 citation statements)

References 5 publications

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“…Primary muscular tuberculosis is a very uncommon condition in both children and adults [ 7 ]. Current knowledge about these conditions is mainly based on case reports because the precise incidence of this disease is not known.…”

Section: Discussionmentioning

confidence: 99%

“…Tuberculosis of muscle presenting as swelling has been mostly reported to present as a mass in a single muscle [ 3 , 10 ]. However, recently skeletal muscle tuberculosis simultaneously involving multiple sites presenting as multiple muscle masses in different parts of the body has also been reported from India [ 7 ]. These case reports highlight the uncommon nature of these conditions.…”

Section: Discussionmentioning

confidence: 99%

“…However, there was no history of contact with tuberculosis and a Mantoux test was negative. It must be highlighted that in previous studies [ 3 , 7 , 10 ] most of the patients were diagnosed as muscular tuberculosis with muscle biopsy and very few of these cases had a positive Mantoux test. In one study of muscular tuberculosis out of 11 patients who underwent a purified protein derivative (PPD) test only one was strongly positive while the other 10 were negative [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…It has been suggested that in an area with high incidence of tuberculosis, muscular tuberculosis should be considered strongly when clinical features like muscular pain and swelling are present even though a chest X-ray is normal and there is no evidence of active foci of tuberculosis elsewhere in the body [ 5 ]. The pathogenesis for multiple intramuscular swellings in this patient with no evidence of active foci of tuberculosis elsewhere could only be explained by reactivation of latent tubercular bacilli at the state of reduced immunity during the active growth period of the child, which had lodged in muscle during period of lymphohematogenous spread of primary tuberculosis [ 2 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Tuberculosis presenting as multiple intramuscular nodules in a child: a case report

Dhakal¹,

Shah²,

Shrestha³

et al. 2015

J Med Case Reports

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IntroductionTuberculosis is a global health problem that mostly affects people in developing countries. Tuberculosis can occur in various organ systems and may present with diverse manifestations in the same system. Primary muscular tuberculosis is a very rare condition in both adults and children, and tuberculosis of various muscle groups presenting as intramuscular nodules is an even more uncommon presentation.Case presentationA 9-year-old Asian girl presented with multiple painless, gradually progressive swellings over different parts of her body for 3 months with no history of contact with tuberculosis. A physical examination was normal except for multiple swellings in her right forearm, a single swelling in her interscapular region and multiple swellings in her right calf. Ultrasonography of swellings revealed multiple nodules in the intramuscular layer. Excisional biopsies performed from two different sites revealed swellings in muscular layers and histopathology showed granulomatous inflammation with caseous necrosis consistent with tuberculosis. The child was started on antitubercular therapy after which the swellings resolved; she was kept on regular follow up.ConclusionsIntramuscular nodules in multiple muscular sites may be the presenting symptoms of tuberculosis of the muscles. Tuberculosis of skeletal muscles should be considered in a differential diagnosis when presented with single or multiple masses even when a chest X-ray is normal and there is no evidence of tubercular foci elsewhere in the body.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Tuberculosis presenting as multiple intramuscular nodules in a child: a case report

Dhakal¹,

Shah²,

Shrestha³

et al. 2015

J Med Case Reports

View full text Add to dashboard Cite

show abstract

“…The reasons for the rarity of skeletal muscle TB may be as follows: i) High levels of lactic acid; ii) not enough reticuloendothelial tissue; iii) not enough lymphatic tissue; and iv) rich blood supply (11,12). Thus, the abovementioned reasons may help to explain the rarity of the DTA.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of a tuberculous abscess on the right side of the diaphragm with contrast-enhanced computed tomography: A case report

Dong

Chen

Wang

2016

Molecular and Clinical Oncology

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Abstract.We herein investigate the case of a patient with a tuberculous diaphragmatic abscess confirmed by pathology. The patient underwent plain computed tomography (CT) examination of the chest and contrast-enhanced abdominal CT examination. The abscess appeared as hypodense mass with thick and irregular wall, which was enhanced on the contrast-enhanced CT images. The shape of the mass resembled an irregular double convex lens. No enlarged lymph nodes were detected on the CT images. The presence of a tuberculous diaphragmatic abscess should be suspected in patients with a diaphragmatic hypodense mass with enhanced thick walls, even when there is absence of enlarged lymph nodes on the CT images.

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Case Report: Tuberculous abscess of the popliteal fossa: A case report

Belhassen,

Khlif,

Ferjani

et al. 2023

F1000Res

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Introduction Tuberculosis of the soft tissues is a rare form of extra pulmonary tuberculosis, and isolated localization in the popliteal fossa is particularly exceptional. Atypical clinical presentation can lead to delayed diagnosis and serious complications. Case report We report the case of a 17-year-old patient who was diagnosed with tuberculosis of the popliteal fossa. He presented with a painful inflammatory swelling of the right popliteal fossa associated with a homolateral inguinal lymph node, without knee joint effusion. Standard chest and knee X-rays were normal, while MRI showed an 8 cm well vascularized, partly liquefied mass in the popliteal fossa, developed in contact with the semimembranosus and medial gastrocnemius muscles, associated with a popliteal lymph node without synovial effusion or thickening. Microbiological tests did not isolate any germs. The diagnosis was made on histological examination after biopsy, which revealed a caseous granuloma surrounded by epithelioid cells. The patient was treated with anti-tuberculosis therapy for 9 months. The clinical and radiological regression of the swelling was observed without recurrence at 2 years of follow-up. Conclusion Any soft tissue abscess should raise suspicion of tuberculosis, especially in endemic countries. The importance of histopathological examination should be emphasized to establish the diagnosis in the absence of signs in favor of a primary localization.

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Skeletal muscle tuberculosis simultaneously involving multiple sites

Cited by 11 publications

References 5 publications

Tuberculosis presenting as multiple intramuscular nodules in a child: a case report

Tuberculosis presenting as multiple intramuscular nodules in a child: a case report

Evaluation of a tuberculous abscess on the right side of the diaphragm with contrast-enhanced computed tomography: A case report

Case Report: Tuberculous abscess of the popliteal fossa: A case report

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