Skin and Lacrimal Drainage System

Yanoff, Myron; Sassani, Joseph W.

doi:10.1016/b978-0-323-04232-1.50011-6

Ocular Pathology 2009

DOI: 10.1016/b978-0-323-04232-1.50011-6

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Skin and Lacrimal Drainage System

Myron Yanoff

Joseph W. Sassani

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Cited by 2 publications

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“…5,6 Histopathologically, it is classified into two types: parenchymal and phlebectatic PH. 7 The first type consists of irregular spaces not lined by endothelium, while the second is characterized by regular spaces with endothelial lining. 7 Regarding the clinical appearance, PH is frequently asymptomatic and thus often represents an incidental diagnosis.…”

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“…7 The first type consists of irregular spaces not lined by endothelium, while the second is characterized by regular spaces with endothelial lining. 7 Regarding the clinical appearance, PH is frequently asymptomatic and thus often represents an incidental diagnosis. 8,9 It is a poorly known condition both to clinicians and radiologists, without pathognomonic imaging features and frequently misdiagnosed, being often confused with other benign and malignant lesions.…”

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MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

Calistri

Nardi

Rastrelli

et al. 2023

Magnetic Resonance Imaging

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BackgroundPeliosis hepatis (PH) is a rare benign condition, characterized by hepatic sinusoidal dilatation and blood‐filled cystic cavities, often found incidentally, with still challenging diagnosis by imaging due to polymorphic appearance.PurposeBased on a retrospective analysis of our series (12 patients) and systematic literature review (1990–2022), to organize data about PH and identify features to improve characterization.Study TypeRetrospective case series and systematic review.PopulationTwelve patients (mean age 48 years, 55% female) with pathology‐proven PH and 49 patients (mean age 52 years, 67% female) identified in 33 studies from the literature (1990–2022).Field Strength/Sequence1,5‐T; T1‐weighted (T1W), T2‐weighted (T2W), diffusion‐weighted (DW), contrast‐enhanced (CE) T1W imaging.AssessmentWe compared our series and literature data in terms of demographic (gender/age/ethnicity), clinical characteristics (symptoms/physical examination/liver test), associated conditions (malignancies/infectious/hematologic/genetic or chronic disorders/drugs or toxic exposure) percentage. On magnetic resonance imaging lesion numbers/shape/mean maximum diameter/location/mass effect/signal intensity were compared. PH pathological type/proposed imaging diagnosis/patient follow‐up were also considered.Statistical TestsJoanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports/Series quality assessment. Intraclass correlation and Cohen's kappa coefficients for levels of inter/intrareader agreement in our experience.ResultsPatients were mainly asymptomatic (92% vs. 70% in our study and literature) with associated conditions (83% vs. 80%). Lesions showed homogeneous T1W‐hypointensity (58% vs. 65%) and T2W‐hyperintensity (58% vs. 66%). Heterogeneous nonspecific (25% vs. 51%), centrifugal (34% vs. 8%), or rim‐like centripetal (25% vs. 23%) patterns of enhancement were most frequent, with hypointensity on the hepatobiliary phase (HBP), without restricted diffusivity. Good inter‐ and intrareader agreement was observed in our experience. Concerning JBI Checklist, 19 out of 31 case reports met at least 7 out of 8 criteria, whereas 2 case series fulfilled 5 and 6 out of 10 items respectively.Data ConclusionA homogeneous, not well‐demarcated T1W‐hypointense and T2W‐hyperintense mass, with heterogeneous nonspecific or rim‐like centripetal or centrifugal pattern of enhancement, and hypointensity on HBP, may be helpful for PH diagnosis. Among associated conditions, malignancies and drug exposures were the most frequent.Level of Evidence4Technical EfficacyStage 2

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confidence: 99%

mentioning

confidence: 99%

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

Calistri

Nardi

Rastrelli

et al. 2023

Magnetic Resonance Imaging

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Cytological Evaluation of Palpebral Lesions

Mondal

Mandal

Chakrabarti

2021

Journal of Microscopy and Ultrastructure

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Context: Eyelids by virtue of its unique histomorphology give rise to multitudes of different pathological conditions. Appropriate preoperative cytological diagnoses of these cases are necessary to determine their optimal therapy. Aims: The aims of this study were to evaluate the utility of various cytological techniques in diagnosing the definite pathology for palpebral lesions and thereby to highlight the drawbacks associated with cytology in this context. Materials and Methods: Fine-needle cytology with or without applying the aspiration was the preferable method. Ulcerated lesions were sampled through scrapings. Results: Totally 62 cases were examined. Cytologically, 22 lesions were diagnosed as nonneoplastic, 38 lesions were neoplastic, and nondiagnostic material was obtained twice. Malignant tumors predominated among the neoplastic cases. Basal cell carcinoma (BCC) was the most common malignancy observed. On histopathological corroboration, benign skin adnexal tumor was found to be the most frequently misinterpreted entity. Two (out of four cases) of those tumors were confirmed as melanocytic nevus and BCC. A single case of squamous cell carcinoma was also cytodiagnostically erred into sebaceous carcinoma. Conclusions: Cytologically palpebral pathologies, including the neoplastic ones, are at times vulnerable to misinterpretation. To avert such dilemma, it is better to readily excise any recurrent lesion, basaloid neoplasm, or any necrohemorrhagic lesion presumptive of overshadowing the neoplastic pathology underneath.

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Skin and Lacrimal Drainage System

Cited by 2 publications

References 295 publications

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

MRI of Peliosis Hepatis: A Case Series Presentation With a 2022 Systematic Literature Update

Cytological Evaluation of Palpebral Lesions

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