Skin and Soft Tissue Infections due to Shewanella algae – An Emerging Pathogen

Srinivas, Jampala; Pillai, M.G.K.; Vinod, Vivek; Rai, Dinesh

doi:10.7860/jcdr/2015/12152.5585

Cited by 22 publications

(14 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reader is referred to the paper by Srinivas et al . [ 38 ] for a prospective study (2010–2014) of Shewanella spp. skin and soft-tissue infections in Kerala, India.…”

Section: Resultsmentioning

confidence: 99%

Shewanella spp. infections in Gran Canaria, Spain: retrospective analysis of 31 cases and a literature review

et al. 2017

View full text Add to dashboard Cite

IntroductionShewanella spp. can cause severe skin and soft-tissue infections, gastrointestinal infections, otitis and bacteraemia, generally upon contact with seawater or consumption of raw seafood. Recently, a new condition termed ‘patera foot’ characterized by acute skin and soft-tissue infection has been described in irregular immigrants arriving to the Canary Islands, Spain, in rudimentary boats. Most infections are caused by a single species, Shewanella algae. The improvement of the diagnostic capabilities in clinical microbiology laboratories has resulted in a growing number of cases being reported worldwide, most of them coming from warm regions.Case presentationIn this work, we reviewed the medical records of all the patients with Shewanella infections in the two university hospitals of Gran Canaria (the Canary Islands, Spain) during the period 2000–2016, resulting in the identification of 31 cases. We also conducted a literature review of Shewanella infections reported worldwide in recent years.ConclusionThis case series suggests that Shewanella infections are nosocomially acquired more frequently than previously thought. In addition, the unexpectedly high proportion of multidrug-resistant isolates raises concerns.

show abstract

“…The reader is referred to the paper by Srinivas et al . [ 38 ] for a prospective study (2010–2014) of Shewanella spp. skin and soft-tissue infections in Kerala, India.…”

Section: Resultsmentioning

confidence: 99%

Shewanella spp. infections in Gran Canaria, Spain: retrospective analysis of 31 cases and a literature review

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Schewanella algae has also been shown to be resistant to cefalosporins and to imipenem [24]. In addition, whole genome sequencing has demonstrated the presence of several beta-lactamases in the S. algae genome [5].…”

Section: Discussionmentioning

confidence: 99%

Genomic analysis reveals the presence of a class D beta-lactamase with broad substrate specificity in animal bite associated Capnocytophaga species

Zangenah

Andersson

Özenci

et al. 2016

Eur J Clin Microbiol Infect Dis

View full text Add to dashboard Cite

Capnocytophga canimorsus and Capnocytophga cynodegmi can be transmitted from cats and dogs to humans, and can cause a wide range of infections including wound infections, sepsis, or endocarditis. We and others recently discovered two new Capnocytophaga species, C. canis and C. stomatis, mainly associated with wound infections. The first-line treatment of animal bite related infections is penicillin, and in case of allergy, doxycycline and trimethoprim/sulfamethoxazole. However, there is a lack of antibiotic susceptibility patterns for animal bite associated Capnocytophaga species. Thus, we set out to study the antibiotic profiles against animal bite associated Capnocytophaga species isolated from wound and blood cultures after cat and dog bites and coupled the findings to whole genome sequencing data. A total of 24 strains were included in the study. Phenotypic analysis of antibiotic resistance was performed with E-tests. The web-based tool ‘Resfinder’ was used to identify resistance genes in the whole genome dataset. Two strains of C. cynodegmi and two strains of the recently discovered C. stomatis were resistant to penicillin (MIC > 24 mg/L) and cephalosporins (MIC > 24 mg/L), and three out of these strains also exhibited resistance to imipenem (MIC = 32 mg/L). Genomic analysis revealed that these strains carried a class D beta-lactamase gene, which has not previously been found in Capnocytophaga spp. A class D beta lactamase with broad substrate specificity was found in animal bite associated Capnocytophaga species, which could have important implications when treating wound infections after cat and dog bites. It also suggests that pet animal bacteria can harbour resistance genes with relevance for human infections.

show abstract

“…It is worth to mention that S . algae is considered the causative agent of skin and soft tissue infections, bacteremia and osteomyelitis 14,15,17 .…”

Section: Resultsmentioning

confidence: 99%

ICE SXT vs. ICESh95: Co-existence of Integrative and Conjugative Elements and Competition for a New Host

Noto

Iriarte

Ramírez

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Integrative and conjugative elements (ICEs) are mobile genetic elements that contribute to horizontal gene transfer. The aim of this work was to study different types of ICEs in clinical isolates of the emergent pathogen Shewanella spp., to compare their transfer efficiency and their ability to integrate a new host. Here we show that 3 out of 10 clinical isolates contained an ICE. Two of these elements were similar to ICEs from the SXT/R391 family and the other one was similar to ICE Sh95 , a hybrid platform. Mating assays showed that these elements co-exist for several generations in the same host. Furthermore, transfer rates and competition assays between ICE Sh95 and ICE Sh392 , an SXT-like element, suggest that the latter has evolved into a well-oiled machine that efficiently spread to different bacteria. Our results provide strong evidence of the role that ICEs play in the dissemination of genetic traits in nature and the implications that they have in the global threat of antimicrobial resistance.

show abstract

Skin and Soft Tissue Infections due to Shewanella algae – An Emerging Pathogen

Cited by 22 publications

References 20 publications

Shewanella spp. infections in Gran Canaria, Spain: retrospective analysis of 31 cases and a literature review

Shewanella spp. infections in Gran Canaria, Spain: retrospective analysis of 31 cases and a literature review

Genomic analysis reveals the presence of a class D beta-lactamase with broad substrate specificity in animal bite associated Capnocytophaga species

ICE SXT vs. ICESh95: Co-existence of Integrative and Conjugative Elements and Competition for a New Host

Contact Info

Product

Resources

About