1998
DOI: 10.1046/j.1525-1497.1998.00009.x
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Skin biopsy techniques for the internist

Abstract: OBJECTIVE:To review three commonly performed skin biopsy procedures: shave, punch, and excision.DATA SOURCES: English-language articles identified through a MEDLINE search (1966-1997) using the MeSH headings skin and biopsy, major dermatology and primary care textbooks, and cross-references. STUDY SELECTION:Articles that reviewed the indications, contraindications, choice of procedure, surgical technique, specimen handling, and wound care. DATA EXTRACTION:Information was manually extracted from all selected ar… Show more

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Cited by 72 publications
(65 citation statements)
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“…Each biopsy specimen demonstrated histologic evidence of NSF, lending validity to our skin scoring system. We intentionally limited our analysis for NSF to a noninvasive skin examination so as to maximize the number of patients who would participate and to avoid the less than trivial infectious complications of a full-thickness (often lower extremity) skin biopsy (20,21), especially given that the patients in this study universally had renal failure and a high prevalence of skin fibrosis and diabetes mellitus, which are known risk factors for surgical wound infection and poor wound healing (22)(23)(24). By not requiring a skin biopsy, we were able to achieve a 94% participation rate and to minimize selection bias.…”
Section: Discussionmentioning
confidence: 99%
“…Each biopsy specimen demonstrated histologic evidence of NSF, lending validity to our skin scoring system. We intentionally limited our analysis for NSF to a noninvasive skin examination so as to maximize the number of patients who would participate and to avoid the less than trivial infectious complications of a full-thickness (often lower extremity) skin biopsy (20,21), especially given that the patients in this study universally had renal failure and a high prevalence of skin fibrosis and diabetes mellitus, which are known risk factors for surgical wound infection and poor wound healing (22)(23)(24). By not requiring a skin biopsy, we were able to achieve a 94% participation rate and to minimize selection bias.…”
Section: Discussionmentioning
confidence: 99%
“…Tensile strength test: the subcutaneous adipose tissue is not always completely severed with every punching procedure, meaning that the whole skin islet can remain in the cutaneous covering or be pulled away from the punch blade when retracting the biopsy punch from the skin [12]. In an attempt to determine the force with which the whole skin islet is held by the subcutaneous tissue, the tensile resistance of the subcutaneous adipose tissue was determined experimentally in another test.…”
Section: 2)mentioning
confidence: 99%
“…However, the medical doctor should have in mind that in some situations, small skin biopsies might cause difficult to the pathologist to establish a diagnose [6][7][8][9].…”
Section: Introductionmentioning
confidence: 99%