Skin Cancer

Abstract

Skin cancer accounts for most malignancies across the globe. They are primarily divided into melanoma and nonmelanoma skin malignancies. Nonmelanoma skin cancer includes basal cell carcinoma and squamous cell carcinoma. Fair skin and chronic ultraviolet B exposure are the most important risk factors. Primary prevention is achieved by avoiding sun exposure and tanning beds.

Body mass index and risk of non-melanoma skin cancer: cumulative evidence from prospective studies

“…In the US alone, it is estimated that in 2012 there were more than 5.4 million NMSCs and 3.3 million persons treated for NMSC2. More than 80% of NMSC incidence could be attributed to ambient ultraviolet (UV) radiation4, and several host features such as fair skin, red hair, melanocytic nevi, and family history have also been identified as risk factors56. The effectiveness of skin cancer screening on reducing mortality is suggested to be low7.…”

“…Regarding the association with skin cancer, previous meta-analyses reported increased risk of melanoma associated with a higher BMI in men but not in women59. Given that melanoma and NMSC share risk factors5, it is plausible that excess body weight would also be associated with NMSC risk.…”

“…Regarding the association with skin cancer, previous meta-analyses reported increased risk of melanoma associated with a higher BMI in men but not in women59. Given that melanoma and NMSC share risk factors5, it is plausible that excess body weight would also be associated with NMSC risk. There have been a number of prospective observational studies that investigated this association, but their findings are inconsistent101112131415161718.…”

Metastatic Cutaneous Squamous Cell Carcinoma with Gastrointestinal Involvement: A Case Report

“…Cutaneous SCC constitutes up to 20% of non-melanoma skin cancers, with principal epidemiologic risk factors that include UV exposure, age, and phenotypic variations (including fair skin, blue eyes, and Northern European origin) [9]. Other less common but significant risk factors include prior therapy with immunosuppressive agents and immunosuppressed populations such as transplant recipients [10].…”

Light and lasers for vascular and skin diseases: From bench to clinic – An update

“…Laser ablation is an alternative, non-surgical treatment modality for skin cancer such as low-risk BCC; however, lack of confirmative tumor destruction or residual tumor presence has been a limiting factor to adoption [25]. Karsai et al [26] verified that 595-nm PDL is an effective and safe method for treating superficial BCC.…”