Skin Cancer—The Importance of Prevention

Linos, Eleni; Katz, Kenneth A.; Colditz, Graham A.

doi:10.1001/jamainternmed.2016.5008

Cited by 49 publications

(42 citation statements)

References 12 publications

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“…Comparing GBD data between countries may also allow evaluation of potential benefits and harms of an intervention. For example, there is currently debate about whether populations should offer organized programmes of skin checks for melanoma early detection/screening . In the absence of evidence from a large population‐based randomized controlled trial on the effects of melanoma screening, the extent of the potential benefits (excision of melanomas which would otherwise have progressed) and harms (including overdiagnosis of lesions which would never have progressed or shortened life) are uncertain .…”

mentioning

confidence: 99%

“…For example, there is currently debate about whether populations should offer organized programmes of skin checks for melanoma early detection/screening. [7][8][9][10][11] In the absence of evidence from a large population-based randomized controlled trial on the effects of melanoma screening, the extent of the potential benefits (excision of melanomas which would otherwise have progressed) and harms (including overdiagnosis of lesions which would never have progressed or shortened life) are uncertain. 7 Melanoma incidence rates have risen in many countries worldwide, 12 which appears to have been largely driven by increased detection of early-stage disease.…”

mentioning

confidence: 99%

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Beyond country-specific incidence and mortality: the global burden of melanoma

Bell

Cust

2018

Br J Dermatol

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mentioning

confidence: 99%

mentioning

confidence: 99%

Beyond country-specific incidence and mortality: the global burden of melanoma

Bell

Cust

2018

Br J Dermatol

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“…The incidence of MM and NMSC is increasing worldwide, becoming an issue for the healthcare systems due to treatment costs and morbidity [8]. The increased rate is related to the fact that in recent years, awareness of this disease has increased among patients and physicians.…”

Section: Discussionmentioning

confidence: 99%

“…It must be highlighted that most of the NMSC appear on sun-exposed areas, such as the face, neck, and upper limbs [11]. These locations can lead to difficulties in the oncologic surgical excision with the best functional and aesthetic outcome [8]. In addition, the lesions can lead topain and pruritus, causing functional limitations [10].…”

Section: Discussionmentioning

confidence: 99%

Quality of Life in Patients with Surgically Removed Skin Tumors

et al. 2020

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Background and Objectives: Skin cancer is one of the most frequently diagnosed malignancies. The main goal of the therapeutic management is total excision with the prevention of recurrence and metastasis. The quality of life of the patients with skin cancer is affected by the morbidity risk, surgery, and cosmetic or functional aspects. The aim of this study was to evaluate the quality of life of patients with skin cancer prior to and post surgical intervention. Material and methods: We performed a prospective study on 247 patients with skin tumors. Quality of life was evaluated through an initial questionnaire that was given to all consenting patients. This was used to determine patients' mobility, selfcare, normal activities, pain, and despair, using a five-point Likert scale. The general autoperceived health state was also recorded using a 100-point scale. The study included the responses of all patients at hospital admission, after one month of surgery, and after one year of surgery. Results: In patients with squamous cell carcinoma (SCC), the general health state indicator statistically significantly decreased one month after surgery and increased at one-year follow-up. In malignant melanoma (MM) patients, mobility, selfcare, normal activities, and discomfort presented a decrease in values one year after surgery, compared to the values registered at hospital admission. In patients with basal cell carcinoma (BCC), all indicators of quality of life presented an impaired value one year after surgery, after a decreasing trend. The general health state indicator statistically significantly increased one month after surgery and after one year. Conclusions: Surgery is one of the main steps in treating skin cancer. It has a great impact on patients' quality of life because of pain andthe effect on mobility and normal activities. Skin cancers influence the quality of life of patients both psychologicallyand physically.

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“…In a punch biopsy, in particular, hollow needles, usually termed BPs, are pressed down into the skin to extract a tissue sample. BPs are the primary medical tools adopted for diagnosing skin disorders [1], such as skin cancer, which has the highest incidence with respect to all other cancers combined in the U.S. [2]. If the punch biopsy is performed incorrectly, a pathologist's interpretation of a skin biopsy can be limited or erroneous.…”

Section: Introductionmentioning

confidence: 99%

Tissue Cutting With Microserrated Biopsy Punches

Giovannini

Ren

Wang

et al. 2017

Journal of Micro and Nano-Manufacturing

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This paper investigates the application of bioinspired serrated cutting edges in tissue cutting by biopsy punches (BPs) to reduce the insertion force. BPs are frequently used as a diagnostic tool in many minimally invasive procedures, for both tissue extraction and the delivery of medical fluids. The proposed work is inspired by the mosquito's maxilla that features microserrations on its cutting edges with the purpose of painlessly puncturing the human skin. The objective of this paper is to study the application of maxillalike microserrations on commercial BPs. The fundamental goal is the minimization of the puncture force at the BP tip during insertion procedures. Microserrations were created on the cutting edge by using a picosecond laser while cutting tests were implemented on a customized testbed on phantom tissue. A reduction of 20–30% in the insertion forces has been achieved with microserrated punches with different texture depths encouraging, thereby, further studies and applications in biomedical devices. Three-dimensional (3D) and two-dimensional (2D) finite element simulations were also developed to investigate the impact of microserrated cutting edges on the stresses in the contact area during soft tissue cutting.

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Skin Cancer—The Importance of Prevention

Cited by 49 publications

References 12 publications

Beyond country-specific incidence and mortality: the global burden of melanoma

Beyond country-specific incidence and mortality: the global burden of melanoma

Quality of Life in Patients with Surgically Removed Skin Tumors

Tissue Cutting With Microserrated Biopsy Punches

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