Skin contamination and low airborne nickel exposure of electroplaters

Bavazzano, P; Bolognesi, R.; Cassinelli, Claudia; Gori, Roberto; Donni, V. Li; Martellini, F.; Oliva, G.; Riccucci, S.

doi:10.1016/0048-9697(94)90363-8

Cited by 11 publications

(13 citation statements)

References 5 publications

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“…Detection limit for serum Ni was 0.2 mg/l. Analytical quality control of urine and serum Ni was carried out on 10% of the samples by neutron activation analysis (8,11). Statistical analysis of the data was made using SYSTAT software.…”

Section: Methodsmentioning

confidence: 99%

“…Studies performed before 1990 report contradictory levels of Ni in biological fluids: this was mainly related to specimen contamination (10). Recently, correct procedures for collection, storage and determination of Ni and other trace elements in human blood and urine have been described (8)(9)(10)(11). Moreover, improved atomic absorption spectrophotometers with a low detection limit for analysis of Ni in biological specimens have been utilized.…”

mentioning

confidence: 99%

“…Moreover, improved atomic absorption spectrophotometers with a low detection limit for analysis of Ni in biological specimens have been utilized. For these reasons, accurate reference values for serum and urine Ni in normal populations were reported (9)(10)(11).…”

mentioning

confidence: 99%

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Serum and urine nickel in nickel‐sensitized women: effects of oral challenge with the metal

Andreassi¹,

Gioacchino

Sabbioni

et al. 1998

Contact Dermatitis

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15 women with a positive patch test only to nickel (Ni) and without atopy and 10 control women were selected for the study. Blood and urine specimens were collected with a standard procedure either before (at 8 a.m.) or 4 and 24 h after the ingestion of 10 mg of Ni (as Ni sulfate). 7 of the Ni-sensitized patients showed a flare-up of eczema and/or urticaria during the test, while the other women were non-symptomatic. Serum and urine Ni of controls and Ni-sensitized women did not significantly differ. Serum and urine Ni levels determined before the oral Ni challenge were in the range of reference values recently reported by other authors (0.2-2.0 micrograms/l of serum or urine). Ni was greatly augmented in urine and serum 4 h after the challenge (25th-75th percentiles: 43-264 micrograms/l urine Ni and 15-52 micrograms/l serum Ni). 24 h after Ni ingestion, urine Ni was 41-153 micrograms/l and serum Ni 4-17 micrograms/l. Our study confirms a previous investigation showing similar levels of serum and urine Ni following ingestion of the metal in control and Ni-sensitized women without atopy.

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Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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Serum and urine nickel in nickel‐sensitized women: effects of oral challenge with the metal

Andreassi¹,

Gioacchino

Sabbioni

et al. 1998

Contact Dermatitis

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“…It offers satisfactory performances due to its low boiling point added to its low polarity. However, many works dealt with the toxic and hazardous effects of this solvent [2][3][4][5], and several investigations were also achieved using alternative solvents with the aim of more effective and greener extraction procedures, safer for users and more environmentally friendly [1,[6][7][8][9][10][11]. Nevertheless, and despite its ranking on top of the list of the hazardous solvent, n-hexane is still the solvent of choice for extraction of aromas.…”

Section: Introductionmentioning

confidence: 99%

Extraction of aroma compounds in blackcurrant buds by alternative solvents: Theoretical and experimental solubility study

Filly

Fabiano‐Tixier

Lemasson³

et al. 2014

Comptes Rendus. Chimie

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“…Previous studies of electroplating workers have often reported poor/no correlations between air and urine metal concentrations 18-20 , although some studies have observed moderate to high correlations (range: r = 0.48–0.96, median: r = 0.68) 21-24 . The relationship between air and urinary measurements likely varies due to the extent of dermal exposure, the use of personal protective equipment, and personal behaviors such as smoking that may transfer the contaminants from hand to mouth, as well as the time of day the urinary measurements are collected in relation to the air measurements 21-22, 25-26 . Subject-specific variations in uptake and metabolic/excretion rates could also reduce the correlation with the post work shift urinary concentrations.…”

Section: Introductionmentioning

confidence: 99%

Reliability and validity of expert assessment based on airborne and urinary measures of nickel and chromium exposure in the electroplating industry

Chen

Coble

Deziel

et al. 2014

J Expo Sci Environ Epidemiol

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The reliability and validity of six experts’ exposure ratings were evaluated for 64 nickel-exposed and 72 chromium-exposed workers from six Shanghai electroplating plants based on airborne and urinary nickel and chromium measurements. Three industrial hygienists and three occupational physicians independently ranked the exposure intensity of each metal on an ordinal scale (1–4) for each worker's job in two rounds: the first round was based on responses to an occupational history questionnaire and the second round also included responses to an electroplating industry-specific questionnaire. Spearman correlation (rs) was used to compare each rating's validity to its corresponding subject-specific arithmetic mean of four airborne or four urinary measurements. Reliability was moderately-high (weighted kappa range=0.60–0.64). Validity was poor to moderate (rs= -0.37–0.46) for both airborne and urinary concentrations of both metals. For airborne nickel concentrations, validity differed by plant. For dichotomized metrics, sensitivity and specificity were higher based on urinary measurements (47–78%) than airborne measurements (16–50%). Few patterns were observed by metal, assessment round, or expert type. These results suggest that, for electroplating exposures, experts can achieve moderately-high agreement and (reasonably) distinguish between low and high exposures when reviewing responses to in-depth questionnaires used in population-based case-control studies.

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Skin contamination and low airborne nickel exposure of electroplaters

Cited by 11 publications

References 5 publications

Serum and urine nickel in nickel‐sensitized women: effects of oral challenge with the metal

Serum and urine nickel in nickel‐sensitized women: effects of oral challenge with the metal

Extraction of aroma compounds in blackcurrant buds by alternative solvents: Theoretical and experimental solubility study

Reliability and validity of expert assessment based on airborne and urinary measures of nickel and chromium exposure in the electroplating industry

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