Skin diseases in the Da Qing Diabetes Study: a cross-sectional study

Abstract

Background: The prevalence of skin diseases and diabetes mellitus (DM) are prominent around the world. The current scope of knowledge regarding the prevalence of skin diseases and comorbidities with type 2 DM (T2DM) is limited, leading to limited recognition of the correlations between skin diseases and T2DM. Methods: We collected 383 subjects from the Da Qing Diabetes Study during the period from July 9th to September 1st, 2016. The subjects were categorized into three groups: Normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and T2DM. The prevalence and clinical characteristics of skin diseases were recorded and investigated. Results: In this cross-sectional study, 383 individuals with ages ranging from 53 to 89-year-old were recruited. The overall prevalence of skin diseases was 93.5%, and 75.7% of individuals had two or more kinds of skin diseases. Additionally, there were 47 kinds of comorbid skin diseases in patients with T2DM, of which eight kinds of skin diseases had a prevalence >10%. The prevalence of skin diseases in NGT, IGT, and T2DM groups were 93.3%, 91.5%, and 96.6%, respectively; stratified analysis by categories showed a statistically significant difference in “disturbances of pigmentation” and “neurological and psychogenic dermatoses”. The duration of T2DM also significantly associated with the prevalence of “disturbances of pigmentation” and “neurological and psychogenic dermatoses”. Subsequently, the prevalence of “disturbances of pigmentation” was higher in males than females in NGT ( P < 0.01) and T2DM ( P < 0.01) groups. In addition, the difference in the prevalence of “disturbances of pigmentation” was also significant in NGT and T2DM groups ( P < 0.01). Conclusions: There was a high prevalence of skin diseases in the Da Qing Diabetes Study. To address the skin diseases in the Da Qing Diabetes Study, increased awareness and intervention measures should be implemented.

The prevalence of metabolic skin diseases in the population with Diabetes Mellitus

“…Para indivíduos diabéticos com idade entre 53 e 89 anos, a prevalência geral de doenças de pele foi de 93,5% e 75,7% dos indivíduos apresentavam dois ou mais tipos de doenças de pele (Shen et al, 2021), também visto que quando classificados em relação a sensibilidade insulínica, de acordo com o nível de glicemia plasmática no jejum: normal, tolerantes ou resistentes, os indivíduos DM foram a maioria em relação á disfunções cutâneas. Ocorrem no total 47 tipos de doenças ou sintomas de pele comórbidos com DM2, nos quais oito apresentaram prevalência >10% e não foram apontados pelo estudo, ocasionando assim baixa qualidade informacional para a pesquisa.…”