Skin elasticity meter or subjective evaluation in scars: a reliability assessment

Draaijers, Lieneke J; Botman, Yvonne A.M; Tempelman, F.R.H.; Kreis, R.W.; Middelkoop, Esther; Zuijlen, Paul P. M. van

doi:10.1016/j.burns.2003.09.003

Cited by 163 publications

(145 citation statements)

References 10 publications

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“…It is akin to a physiological vaginal stressor, like a Valsalva abdominal straining effort. Prior studies on skin diseases have reported on its safety and lack of pain during the measurements [12][13], observations that could not be confirmed in this study, as it was done under anesthesia.…”

Section: Discussioncontrasting

confidence: 66%

“…The reliability of the Cutometer® has been tested on normal skin [12] and on patients with scleroderma lesions [13]. There are several other clinical reports of the use of the Cutometer® or cutometer-like devices to examine eyelid laxity, laser resurfacing, burns and scar formation and other skin conditions [11].…”

Section: Discussionmentioning

confidence: 99%

“…Three cycles were used for each measurement but again, all tests were done by the same tester without information on intra-rater reliability [10]. Intra-and inter-rater reliability were tested in the study of skin scarring with the Cutometer® MPA 580 [12]. No data relating to reproducibility of vaginal wall measurements were mentioned in this report.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

n Vivo Btc-2000™ Measurement of Anterior Vaginal Wall Biomechanical Properties in Prolapse Patients Undergoing Surgical Repair

Mosier¹,

Jerome²,

Xie³

2011

J Biotechnol Biomaterial

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Section: Discussioncontrasting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

n Vivo Btc-2000™ Measurement of Anterior Vaginal Wall Biomechanical Properties in Prolapse Patients Undergoing Surgical Repair

Mosier¹,

Jerome²,

Xie³

2011

J Biotechnol Biomaterial

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“…1,2 Most of the scar characteristics that can be distinguished (e.g., thickness, relief, pliability and surface area/contraction) are largely affected by the aberrant type of collagen that is present in scars. [3][4][5] Accordingly, treatment modalities are considered to influence the scar's morphometry (i.e., collagen), and therefore, it would be desirable to have a noninvasive imaging device, providing absolute structural information on collagen.…”

Section: Introductionmentioning

confidence: 99%

In vivo polarization-sensitive optical coherence tomography of human burn scars: birefringence quantification and correspondence with histologically determined collagen density

Jaspers

Feroldi²,

Vlig

et al. 2017

J. Biomed. Opt.

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In vivo polarization-sensitive optical coherence tomography of human burn scars: birefringence quantification and correspondence with histologically determined collagen density," J. Biomed. Opt. Abstract. Obtaining adequate information on scar characteristics is important for monitoring their evolution and the effectiveness of clinical treatment. The aberrant type of collagen in scars may give rise to specific birefringent properties, which can be determined using polarization-sensitive optical coherence tomography (PS-OCT). The aim of this pilot study was to evaluate a method to quantify the birefringence of the scanned volume and correlate it with the collagen density as measured from histological slides. Five human burn scars were measured in vivo using a handheld probe and custom-made PS-OCT system. The local retardation caused by the tissue birefringence was extracted using the Jones formalism. To compare the samples, histograms of birefringence values of each volume were produced. After imaging, punch biopsies were harvested from the scar area of interest and sent in for histological evaluation using Herovici polychrome staining. Two-dimensional en face maps showed higher birefringence in scars compared to healthy skin. The Pearson's correlation coefficient for the collagen density as measured by histology versus the measured birefringence was calculated at r ¼ 0.80 (p ¼ 0.105). In conclusion, the custom-made PS-OCT system was capable of in vivo imaging and quantifying the birefringence of human burn scars, and a nonsignificant correlation between PS-OCT birefringence and histological collagen density was found.

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“…7,12 The mechanical properties of the skin tissue so far have been measured by applying deformation forces, including traction, tension, suction, torsion or indentation in various ways to the skin samples. 11,13,14 Uniaxial extension setups are beneficial as the can be used to evaluate in-plane directional differences in material properties and can be non-invasive, applicable and easy to use in vivo. 15 Characterization of the mechanical properties of murine (rat or mice) skin would be important to allow its use as an animal model for human skin diseases.…”

Section: Introductionmentioning

confidence: 99%

Mechanical characterization of the rat and mice skin tissues using histostructural and uniaxial data

2015

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The skin tissue has been shown to behave like a nonlinear anisotropic material. This study was aimed to employ a constitutive fiber family equation to characterize the nonlinear anisotropic mechanical behavior of the rat and mice skin tissues in different anatomical locations, including the abdomen and back, using histostructural and uniaxial data. The rat and mice skin tissues were excised from the animals' body and then the histological analyses were performed on each skin type to determine the mean fiber orientation angle. Afterward, the preconditioned skin tissues were subjected to a series of quasi-static axial and circumferential loads until the incidence of failure. The crucial role of fiber orientation was explicitly added into a proposed strain energy density function. The material coefficients were determined using the constrained nonlinear optimization method based on the axial and circumferential extension data of the rat and mice samples at different anatomical locations. The material coefficients of the skins were given with R 2 0.998. The results revealed a significant load-bearing capacity and stiffness of the rat abdomen compared to the rat back tissues. In addition, the mice abdomen showed a higher stiffness in the axial direction in comparison with circumferential one, while the mice back displayed its highest stiffness in the circumferential direction. The material coefficients of the rat and mice skin tissues were determined and well compared to the experimental data. The optimized fiber angles were also compared to the experimental histological data, and in all cases less than 11.85% differences were observed in both the skin tissues.

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Skin elasticity meter or subjective evaluation in scars: a reliability assessment

Cited by 163 publications

References 10 publications

n Vivo Btc-2000™ Measurement of Anterior Vaginal Wall Biomechanical Properties in Prolapse Patients Undergoing Surgical Repair

n Vivo Btc-2000™ Measurement of Anterior Vaginal Wall Biomechanical Properties in Prolapse Patients Undergoing Surgical Repair

In vivo polarization-sensitive optical coherence tomography of human burn scars: birefringence quantification and correspondence with histologically determined collagen density

Mechanical characterization of the rat and mice skin tissues using histostructural and uniaxial data

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