Skin glues for wound closure

Marshall, Geofrey

doi:10.18773/austprescr.2013.023

Cited by 6 publications

(6 citation statements)

References 10 publications

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“…Due to its electron-repelling nitrile group, the acrylic compound is susceptible to nucleophilic attack by weak bases such as water or amines [ 5 ]. In an exothermic reaction, this creates a stable cross-link with the skin [ 4 ].…”

Section: Categories Of Tissue Adhesivesmentioning

confidence: 99%

“…Some characteristics of the Polycyanoacrylates compounds can be directly affected by their carbon side chains. For instance, the longer carbon side chains provide more flexibility and stability for these compounds [ 2 , 4 ].…”

Section: Categories Of Tissue Adhesivesmentioning

confidence: 99%

“…The material is water-soluble and binds even to moist surfaces [ 28 ]. Sufficient elasticity and ductility are also among their advantages [ 4 ]. However, a major safety risk is the particularly high swelling index, whereby PEG-based materials can swell up to 400% of their original size, compressing nerves and vessels in the immediate vicinity and clogging application materials [ 5 ].…”

Section: Categories Of Tissue Adhesivesmentioning

confidence: 99%

“…Synthetic and biological sutures as well as absorbable and non-absorbable sutures are used in this process. Appropriate tensile strength and low dehiscence are important here [ 2 , 4 ]. In addition, the penetration of healthy tissue creates a possible entry portal for pathogens, thus increasing the risk of infection [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

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Tissue Adhesives in Reconstructive and Aesthetic Surgery—Application of Silk Fibroin-Based Biomaterials

Smeets

Tauer

Vollkommer

et al. 2022

IJMS

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Tissue adhesives have been successfully used in various kind of surgeries such as oral and maxillofacial surgery for some time. They serve as a substitute for suturing of tissues and shorten treatment time. Besides synthetic-based adhesives, a number of biological-based formulations are finding their way into research and clinical application. In natural adhesives, proteins play a crucial role, mediating adhesion and cohesion at the same time. Silk fibroin, as a natural biomaterial, represents an interesting alternative to conventional medical adhesives. Here, the most commonly used bioadhesives as well as the potential of silk fibroin as natural adhesives will be discussed.

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Section: Categories Of Tissue Adhesivesmentioning

confidence: 99%

Section: Categories Of Tissue Adhesivesmentioning

confidence: 99%

Section: Categories Of Tissue Adhesivesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Tissue Adhesives in Reconstructive and Aesthetic Surgery—Application of Silk Fibroin-Based Biomaterials

Smeets

Tauer

Vollkommer

et al. 2022

IJMS

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“…Today's products are all effective and nontoxic and produce stronger bonds. One study has shown that the current adhesive properties have a bursting strength equivalent to 4/0 nylon in an intracuticular wound closure [3] .…”

Section: Figure 1: Surgical Glue and Its Repairmentioning

confidence: 99%

Surgical glue- a promising technology for wound healing

Krishna¹,

Maheswari²,

G³

2018

Int. J. Res. Pharm. Sci & Tech.

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Wound closure is one of the important steps of surgical dressing and suturing is the most commonly used method of wound closure. The process of suturing takes very long time for surgery and increases the patient’s risk of anesthesia awareness. Skin glues are a safe and effective method to close selected wounds. They are also cost-effective and help prevent infection. Ideally, wounds should be less than 4 cm, not contaminated or infected and have skin edges that are not under tension. Wounds should be closed within 12 hours. Novel methods of wound closure have been introduced to address these issues, most notably cyanoacrylate tissue glues. The evidence would suggest that the use of cyanoacrylate tissue glue is associated with a reduction in closure time and costs. On a daily basis, dermasurgeons are facing different kinds of wounds that have to be closed. With a plethora of skin closure materials currently available, choosing a solution that combines excellent and rapid cosmetic results with practicality and cost-effectiveness is preferred.

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