Skin: Graft adherence to de-epithelialized surfaces: a comparative study

Tavis, Michael J.

doi:10.1097/00006534-197709000-00109

Cited by 6 publications

(5 citation statements)

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“…In the rabbit, capillaries from the host site grew into the graft by day 4. [20][21][22] In the rat model, revascularization occurred 2 days after graft placement; this was validated by ATP and glucose level. 23 Normally, after approximately 5 days, capillary loops are established with unidirectional blood flow.…”

Section: Discussionmentioning

confidence: 99%

Prelaminated Fasciomucosal Flap Using Tongue Mucosa in a Rat Model

Ahn

Kim²,

Lee³

2003

J reconstr Microsurg

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Reconstruction of tongue defects from various causes has been a continuing challenge to reconstructive surgeons. If tongue mucosa is used in tongue reconstruction, some disadvantages of cutaneous flaps can be overcome, and also some functions of the tongue, like handling, compressing, and macerating of food, can be improved. The purpose of this study was to assess the feasibility of a prelaminated fasciomucosal flap, using rat tongue mucosa. The survival rate of prelamination and revascularization of the dorsal tongue mucosa graft was evaluated. Changes in the epithelial cell layer and tongue papilla over time were observed. Tongue mucosa graft prelamination was feasible in most cases, and the survival rate was 83.3 percent. The number of microvessels increased with time, and statistically significant positive correlations were observed (Spearman rank correlation rs =0.709 p<0.05). The results validated that it is possible to fabricate a fasciomucosal flap using tongue mucosa. However, the prelaminated flap should be transferred to the recipient site between 10 and 14 days after prelamination, to maintain the papillary morphology of the tongue.

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Section: Discussionmentioning

confidence: 99%

Prelaminated Fasciomucosal Flap Using Tongue Mucosa in a Rat Model

Ahn

Kim²,

Lee³

2003

J reconstr Microsurg

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“…We cannot say with certainty that application of a homograft before discontinuing thrombolytic/fibrinolytic therapy would be as successful. However, we suspect that because adherence of the graft to the deepithelialized surface has been shown to be fibrin dependent, 16 the homograft placed on the wound during TPA administration may become problematic. Nevertheless, we do advise administering compensatory transfusions in this setting because the combined risk of reversing the anticoagulation and discontinuing the thrombolytic therapy prematurely in most cases will outweigh the risks of untreated compartment syndrome and infectious complications associated with the transfusion of blood products and/or homograft placement.…”

Section: Discussionmentioning

confidence: 99%

Management Strategy for Compartment Syndrome of the Upper Extremity Arising During Anticoagulation or Thrombolytic Therapy: An Increasingly Common Surgical Dilemma

Newman

Kent

Clair

et al. 2003

Annals of Plastic Surgery

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Compartment syndrome is a documented and potentially lethal complication of thrombolytic therapy. With the increasing use of catheter-directed thrombolytic therapy, a high index of suspicion for the potential occurrence of this surgical emergency must be maintained. Errors of omission in the diagnosis of compartment syndrome, even for a few hours, may lead rapidly to limb loss, renal failure, and possibly death. The authors present a case of compartment syndrome arising in the forearm of a patient being treated with continuous catheter-directed thrombolytic therapy for an occluded arterial bypass graft associated with an ischemic lower extremity. Specific to this presentation is their management of compartment syndrome during thrombolytic therapy as well as previously unreported use of a homograft (cadaveric skin) to control ongoing blood loss from a fasciotomy site in this fully anticoagulated patient. The authors think their management in this case may help to provide direction to others faced with a similar, increasingly common, surgical dilemma.

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“…The adherence is maintained by fibrin layer. Phase 2: it commences after 72 hours because of the fibrous ingrowth and vascular anastomoses [7].…”

Section: Fixation Of Skin Graftsmentioning

confidence: 99%

Skin Graft Fixation and Methods

Rajaram¹,

Sundar²

2022

Skin Grafts for Successful Wound Closure

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Skin graft fixation constitutes the most important element for the success of the reconstruction. The stability of the skin graft over the wound is a determinant factor for its survival. Many techniques have been described in the literature for fixing the skin graft. The most frequent of the techniques is the tie over technique. Staples, fibrin glue are other advancements in the arena of skin graft fixation. The skin graft is covered by a dressing material which keeps it undisturbed and protects the graft from infection. The quest for an ideal dressing material has led to many innovative materials and methods to apply them.

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Skin: Graft adherence to de-epithelialized surfaces: a comparative study

Cited by 6 publications

References 0 publications

Prelaminated Fasciomucosal Flap Using Tongue Mucosa in a Rat Model

Prelaminated Fasciomucosal Flap Using Tongue Mucosa in a Rat Model

Management Strategy for Compartment Syndrome of the Upper Extremity Arising During Anticoagulation or Thrombolytic Therapy: An Increasingly Common Surgical Dilemma

Skin Graft Fixation and Methods

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