Skin, Hair, and Nails

Sundberg, John P.; King, Lloyd E.; Kuiper, Raoul V.

doi:10.1002/9781119624608.ch10

Cited by 1 publication

(2 citation statements)

References 288 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2,42,55 Figures and descriptions of normal mouse skin and adnexa are available from multiple sources. 46,83,88,90…”

Section: Transmission Electron Microscopymentioning

confidence: 99%

“…Skin and adnexal diseases are commonly clustered based on major types of lesions such as diseases of glands, scaly skin diseases with (psoriasiform) or without (ichthyosiform) inflammation, blistering diseases, nail diseases, and many others. 51,[89][90][91] These broad classifications provide a useful starting structure for more detailed evaluations, as defined in both human and veterinary medicine, to obtain a definitive diagnosis. A good place to start are several of the large, multivolume, human dermatopathology textbooks, many of which have an animal models (primarily mouse) section.…”

Section: Comparative Pathologymentioning

confidence: 99%

See 1 more Smart Citation

Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex

Sundberg

Rice

2023

Vet Pathol

Self Cite

View full text Add to dashboard Cite

The skin and adnexa can be difficult to interpret because they change dramatically with the hair cycle throughout life. However, a variety of methods are commonly available to collect skin and perform assays that can be useful for figuring out morphological and molecular changes. This overview provides information on basic approaches to evaluate skin and its molecular phenotype, with references for more detail, and interpretation of results on the skin and adnexa in the mouse. These approaches range from mouse genetic nomenclature, setting up a cutaneous phenotyping study, skin grafts, hair follicle reconstitution, wax stripping, electron microscopy, and Köbner reaction to very specific approaches such as lipid and protein analyses on a large scale.

show abstract

“…2,42,55 Figures and descriptions of normal mouse skin and adnexa are available from multiple sources. 46,83,88,90…”

Section: Transmission Electron Microscopymentioning

confidence: 99%

Section: Comparative Pathologymentioning

confidence: 99%