2021
DOI: 10.1159/000519367
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Skin Lesions, Skin Care, and Characteristics of Pruritus in Patients Undergoing Haemodialysis

Abstract: <b><i>Introduction:</i></b> Pruritus has been shown to be a common and burdensome complaint in the general population. In some diseases, there is an even higher rate and intensity of pruritus such as in chronic kidney diseases. In particular, patients requiring dialysis commonly suffer from pruritus with proportions between 22.0 and 90.0%. Few data on the characteristics and burden of such pruritus have been published. Therefore, the aim of this study was to investigate the extent and p… Show more

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Cited by 5 publications
(4 citation statements)
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“…Little is known about how these approaches work from patients' perspectives. Some have reported that fewer than 40% of patients with uraemic pruritus sought medical help, and fewer than 60% of these patients reported some level of self‐care to their healthcare providers (Gela & Mengistu, 2018; Sommer et al, 2022). These data raise the question of how patients manage uraemic pruritus by themselves.…”
Section: Literature Reviewmentioning
confidence: 99%
See 1 more Smart Citation
“…Little is known about how these approaches work from patients' perspectives. Some have reported that fewer than 40% of patients with uraemic pruritus sought medical help, and fewer than 60% of these patients reported some level of self‐care to their healthcare providers (Gela & Mengistu, 2018; Sommer et al, 2022). These data raise the question of how patients manage uraemic pruritus by themselves.…”
Section: Literature Reviewmentioning
confidence: 99%
“…The itch is described as an irritating sensation in the skin and itching as a situation in which patients experience skin itch (Tarp et al, 2017). Its prevalence rate ranges from 26% to 61% (Nakamoto et al, 2019; Sommer et al, 2022; Sukul et al, 2021), with 40%–61% of patients experiencing moderate to severe pruritus on their backs, extremities and abdomens (D. Kim & Pollock, 2021; Shirazian et al, 2017; Sommer et al, 2022). Uraemic pruritus often has significant physical, social, and psychological impacts on patients and unsatisfactory treatment outcomes (Elhag et al, 2022; D. Kim & Pollock, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…Xerosis and pruritus are common chronic dermatological disorders among patients undergoing maintenance renal dialysis 1 , 2 and in diabetic patients. 3 In patients with end-stage renal disease, dry skin is observed in 50% to 90%, persisting or even worsening despite dialysis where it affects up to 80% of the patients.…”
Section: Introductionmentioning
confidence: 99%
“… 4 Uremic pruritus, for which the etiopathogenesis remains unclear, is also reported in 12% to 90% of these patients and is more severe in patients with dry skin than in those with normal skin. 2 , 5 , 6 Several underlying causes have been proposed, including skin dryness, hypervitaminosis A, mast cell accumulation (increase in histamine release), disturbance in tryptase and chymase activity (pH increase in the stratum corneum ), uremic toxins, allergic sensitization related to dialysis, imbalance in divalent ions, peripheral neuropathy, and opioid system involvement. 7–9 Xerosis, called uremic xerosis in these patients, is not the primary cause of pruritus.…”
Section: Introductionmentioning
confidence: 99%