Skin Manifestations of Paediatric Metabolic Syndrome

Holzer, Gregor; Volc‐Platzer, Beatrix

doi:10.1002/9781119142812.ch72

Cited by 2 publications

(3 citation statements)

References 197 publications

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“…To evaluate children's abdominal fat, the values above the 80 th percentile were considered as abdominal obesity. [ 5 6 9 ] As for BMI, the World Health Organization (WHO) curves were used to identify a child's excess weight. [ 5 6 9 ]…”

Section: Methodsmentioning

confidence: 99%

“…[ 5 6 9 ] As for BMI, the World Health Organization (WHO) curves were used to identify a child's excess weight. [ 5 6 9 ]…”

Section: Methodsmentioning

confidence: 99%

“…[ 1 ] Recently, the link of skin signs of hyperandrogenemia (acne vulgaris, hirsutism and androgenetic alopecia) with obesity and/or metabolic syndrome in the pediatric age group has been explored; however, it needs further biochemical evidence. [ 5 ] Mehta-Ambalal S[ 6 ] found a very high prevalence of altered biochemical, metabolic and hormonal status among female adults with acne. In addition, the polymorphic presentations, biochemical/hormonal evaluations and treatment differ among the various age groups of children.…”

Section: Introductionmentioning

confidence: 99%

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An Observational Study of Clinical, Metabolic and Hormonal Profile of Pediatric Acne

Pareek¹,

Khunger²,

Sharma³

et al. 2022

Indian Journal of Dermatology

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Objectives: To study the biochemical, metabolic and hormonal profile among children presenting with acne and to determine the correlation of these parameters with acne grading. Methods: The observational cross-sectional study was conducted for a duration of 18 months on a total of 50 children between 1 and 12 years of age with clinical features of acne. The detailed information regarding the type of acne, biochemical profile (lipid profile, blood sugar levels), hormonal profile and associated illnesses were recorded. Spearman's rank correlation coefficient was used to find out the correlation of acne grading with hormonal and metabolic changes. Results: The mean age of the children was 11.4 years. Among the various lesions, comedones were seen in 98% cases, papules in 94.00% cases, a scar in 14.00% and pustule in 4.00% cases. As compared to children of age 1-7 years, those in age group 8-12 years had significantly more comedones (48 vs 1, P = 0.04), significantly fewer pustules (0.00% vs 100.00%, P = 0.001), and a comparable number of papules and scars. Most of the children (88.00%) had acne vulgaris grade 1. There was a significant negative correlation of Blood sugar-fasting (r = -0.312, P = 0.0275) and a significant positive correlation of HDL (r = 0.28, P = 0.0491) with acne grading. Conclusion: Comedones and papules are the commonest and the earliest forms of pediatric acne. Severe forms of acne are rarely seen below 12 years, age group. Preadolescent acne is commoner than mid-childhood acne, with no difference between male and females. Blood sugar levels and lipid profile derangements have a weak correlation with acne grading.

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Section: Methodsmentioning

confidence: 99%

“…[ 5 6 9 ] As for BMI, the World Health Organization (WHO) curves were used to identify a child's excess weight. [ 5 6 9 ]…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An Observational Study of Clinical, Metabolic and Hormonal Profile of Pediatric Acne

Pareek¹,

Khunger²,

Sharma³

et al. 2022

Indian Journal of Dermatology

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A Case Report of Xanthoma in a Child: A Sign of Systemic Disease

Katakam,

Sunki,

Netha

et al. 2023

Indian Journal of Paediatric Dermatology

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Xanthomas are localized lipid deposits within an organ system. They are often an important sign of systemic disease. An 11-year-old boy came with complaints of multiple asymptomatic raised lesions over elbows, hands, and knees for 1 year. Lipid profile showed increased levels (total serum cholesterol of 622.2 mg%). Biopsy was suggestive of tuberous xanthoma. His parent’s cholesterol levels were also elevated. Familial hypercholesterolemia (FH) is a common genetic disease in which high low-density lipoprotein cholesterol levels are seen from the birth, and patients are at high risk for cardiovascular disease, cerebrovascular accidents, metabolic syndrome, and premature coronary death. Early detection of FH and early treatment is imperative to reduce morbidity and mortality.

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Skin Manifestations of Paediatric Metabolic Syndrome

Cited by 2 publications

References 197 publications

An Observational Study of Clinical, Metabolic and Hormonal Profile of Pediatric Acne

An Observational Study of Clinical, Metabolic and Hormonal Profile of Pediatric Acne

A Case Report of Xanthoma in a Child: A Sign of Systemic Disease

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