Skin-Moisturizing Effect of Collagen Peptides Taking Orally

Abstract

The skin is said to be "a mirror reflecting who you are inside". Indeed, beauty is not simply one's external appearance, but it also comes from within; beauty also comes from paying attention to both physical and mental health. Attention to have attractive skin has been on the rise in many age groups over the last decade; even women in their 20's often expresses the desire to look younger and fresher. Products containing collagen peptides drive the growth of the health and beauty and food and beverage industry. These products moisturize the skin, leading to their widespread popularity. Oral intake of collagen peptides has been found to increase the moisture content of the stratum corneum, thereby increasing the moisturizing capacity of the skin. Hydroxyproline (Hyp), produced as a result of digesting collagen peptides, increases the expression of serine palmitoyltransferase-2 and β-glucocerebrosidase, enzymes involved in ceramide synthesis in the stratum corneum. When taken orally, collagen peptides are absorbed by the body as Hyp or dipeptide, and this is believed to improve the moisturizing capacity of the skin by increasing the amount of ceramides in the stratum corneum. Consuming foods that beautify the skin is essential to maintain beautiful and healthy skin. Ingredients with skin-enhancing effects are absorbed by the body when ingested as food, and then distributed throughout the skin. This provides effective skin clarifying and anti-aging benefits. Substances that offer these actions are attracting the attention of not only consumers but also researchers interested in the science of beauty.

Oral Intake of Enzymatically Decomposed AP Collagen Peptides Improves Skin Moisture and Ceramide and Natural Moisturizing Factor Contents in the Stratum Corneum

“…Ceramide content was decreased in mouse model of skin photoaging, in which skin barrier damage was induced and remained similar to the normal group when fish collagen was administered [35]. Treatment of three-dimensional cultured human skin models with collagen peptides increased the transcript-level expression of ceramide synthases, such as serine palmitoyltransferase-2 and β-glucocerebrosidase [36]. These results suggest that collagen retained the total ceramide content by maintaining lipid profile in the skin [35].…”

Effectiveness of Dietary Supplement for Skin Moisturizing in Healthy Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

“…The oral intake of collagen peptides has been found to increase the moisturizing capacity of the skin by enhancing the moisture content of the stratum corneum. Collagen is well absorbed into the body in the form of amino acids (AA), dipeptides, and tripeptides after ingestion via the oral route ( 95 ). Some research works have displayed the remarkable absorption of two main CPs, i.e., prolyl-hydroxyproline (Pro–Hyp) and hydroxyprolyl-glycine (Hyp–Gly) that exert chemotaxis on dermal fibroblasts and reinforce cellular proliferative ability ( 27 ).…”

Insights into Bioactive Peptides in Cosmetics

“…Rice-derived peptides (molecular weight < 300 Da) obtained after special processing of rice-bran protein, greatly inhibit activity of MMPs and stimulate the expression of hyaluronan synthase 2 genes in human keratinocytes cells [24]. Manosroi et al (2012) successfully produced formulas containing niosomes encapsulated in rice-bran peptides, and demonstrated that they have ideal clinical anti-aging properties [25].…”