Skin necrosis after extravasation of intravenous vancomycin in a 1-month-old infant: A case report and description of treatment options

Ahmadli, Robabeh; Farshadpour, Narges; Kaffash, Zahra; Mohammadbeigi, Abolfazl

doi:10.4103/jcn.jcn_108_18

Cited by 3 publications

(10 citation statements)

References 7 publications

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“…First aid interventions were primarily used in conjunction with medical, surgical, and dressing interventions. First aid interventions, as shown in Figure 2a, were identified in 26 studies 16–36 . Stopping the IV and removal was the most common intervention, 16–19,22,23,25,26,28–31,34,35 followed by elevation 16,17,19–21,24–26,28,29,31,32 and compression 17,27,29,31–33,36 …”

Section: Resultsmentioning

confidence: 99%

“…First aid interventions, as shown in Figure 2a, were identified in 26 studies. Stopping the IV and removal was the most common intervention, [16][17][18][19]22,23,25,26,[28][29][30][31]34,35 followed by elevation 16,17,[19][20][21][24][25][26]28,29,31,32 and compression. 17,27,29,[31][32][33]36 F I G U R E 1 Preferred Reporting Items for Systematic Reviews and Meta-Analyses systematic review flow chart.…”

Section: First Aidmentioning

confidence: 99%

“…16,17,[19][20][21][22][23][24][25]27,28,[30][31][32][33][34][35][36][37][38][40][41][42] Surgical puncture 17,[21][22][23]25,28,30,31,33,35,37,[40][41][42] and surgical cleaning 17,21,23,25,28,[30][31][32][33]35,37,40,41 were most routinely used among the studies. Moreover, debridement, 16,17,…”

Section: Surgicalmentioning

confidence: 99%

“…The use of dressings as an intervention, as shown in Figure 2d, was evident within 21 studies. 16,17,19,[22][23][24][25][27][28][29][30][31][32][33][34][36][37][38][40][41][42] Moist gauze (saline/iodine) was the most used dressing, followed by foam, silicone-based, silver, and hydrocolloid dressings. Dressings used throughout the studies were primarily used after the extravasation injury had been managed with alternative interventions.…”

Section: Dressingsmentioning

confidence: 99%

“…As shown in Table 3, 21 studies identified what was caused by the extravasation prior to treatment, [16][17][18][19][20][21][22][23]25,26,[31][32][33][34][35][36][37][39][40][41][42] which most commonly included swelling, [17][18][19]26,33,36,[40][41][42] blisters, 16,17,20,25,33,37,40,42 pain, 16,23,26,36,42 skin necrosis, 16,[20][21][22]25,[32][33][34]…”

Section: Extravasation Sequelaementioning

confidence: 99%

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Extravasation injury management for neonates and children: A systematic review and aggregated case series

Dufficy

Takashima

Cunninghame

et al. 2022

Journal of Hospital Medicine

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Background: Pediatric extravasation injuries are significant healthcare-associated injuries, with sometimes significant sequelae. Evidence-based guidance on management is necessary to prevent permanent injury.Purpose: A systematic review of the literature, including aggregated case series, investigating extravasation injury management of hospitalized pediatric patients. Data Sources: PubMed, Cummulative Index to Nursing and Allied Health Literature (CINAHL), and Excerpta Medica database (EMBASE) were searched on December 13, 2021. Study Selection: Primary research investigating extravasation injury management of hospitalized pediatric patients (to 18 years), published from 2010 onwards and in English, independently screened by two authors, with arbitration from a third author. Data Extraction: Data regarding the study, patient (age, primary diagnosis), extravasation (site, presentation, outcome), and treatment (first aid, wound management) were extracted by two authors, with arbitration from a third author.Data Synthesis: From an initial 1769 articles, 27 studies were included with extractable case data reported in 18 studies, resulting in 33 cases. No clinical trials were identified, instead, studies were primarily case studies (52%) of neonates (67%), with varied extravasation symptoms. Studies had good selection and ascertainment, but few met the causality and reporting requirements for quality assessments. Signs and symptoms varied, with scarring (45%) and necrosis (30%) commonly described.Diverse treatments were categorized into first aid, medical, surgical, and dressings.Conclusions: Despite infiltration and extravasation injuries being common within pediatric healthcare, management interventions are under-researched, with low-quality studies and no consensus on treatments or outcomes.

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Section: Resultsmentioning

confidence: 99%

Section: First Aidmentioning

confidence: 99%

Section: Surgicalmentioning

confidence: 99%

Section: Dressingsmentioning

confidence: 99%

Section: Extravasation Sequelaementioning

confidence: 99%

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Extravasation injury management for neonates and children: A systematic review and aggregated case series

Dufficy

Takashima

Cunninghame

et al. 2022

Journal of Hospital Medicine

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Vancomycin

2019

Reactions Weekly

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Development of an Evidence-Based List of Non-Antineoplastic Vesicants

Gorski,

Ong,

Van Gerpen

et al. 2024

Journal of Infusion Nursing

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Infiltration of a vesicant, called extravasation, can result in severe patient injuries. Recognition of vesicants and their relative risk of injury is essential to extravasation prevention, early recognition, and appropriate treatment. In this article, the Vesicant Task Force (VTF) updates the previously published Infusion Nurses Society (INS) vesicant list from 2017. The 2024 INS list diverges from earlier vesicant lists, such as the 2017 VTF list, by adopting a risk stratification approach based upon documented patient outcomes, in contrast to the reliance on expert consensus or only surrogate risk indicators, such as pH and osmolarity. The methodology used to create the updated list is explained, and the criteria for high- and moderate-risk vesicants and cautionary vesicants are defined.

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Skin necrosis after extravasation of intravenous vancomycin in a 1-month-old infant: A case report and description of treatment options

Cited by 3 publications

References 7 publications

Extravasation injury management for neonates and children: A systematic review and aggregated case series

Extravasation injury management for neonates and children: A systematic review and aggregated case series

Vancomycin

Development of an Evidence-Based List of Non-Antineoplastic Vesicants

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