2001
DOI: 10.1034/j.1399-3038.2001.012002087.x
|View full text |Cite
|
Sign up to set email alerts
|

Skin‐prick test findings in students from moisture‐ and mould‐damaged schools:
A 3‐year follow‐up study

Abstract: Dampness and moisture problems in a building may cause growth of moulds, leading to sensitization and symptoms in the inhabitants. The mechanism by which sensitization to moulds takes place has remained obscure; in particular, the role of atopy is not clear. In 1996, 622 pupils (7-13 years of age) attending a school with a moisture problem (index school; 414 pupils) and a control school (208 pupils) were screened using a questionnaire. Two-hundred and twelve children had doctor-diagnosed asthma, parental-repor… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

2
39
1
2

Year Published

2004
2004
2017
2017

Publication Types

Select...
9

Relationship

3
6

Authors

Journals

citations
Cited by 37 publications
(44 citation statements)
references
References 13 publications
2
39
1
2
Order By: Relevance
“…The lack of germinability of microconidia and the importance of exposure to airflow or mechanical handling to cause particle aerosolization may be reasons why, as concluded in a review paper, B. cinerea is not measured to be among the dominating fungi in indoor air (26). The facts that B. cinerea is able to grow on building materials and on many common fruits and vegetables, that it produces microconidia and particles smaller than conidial size, and that relatively many people are allergic to B. cinerea (24,27,30,31) may indicate that exposure to B. cinerea is more common than what has been measured in exposure studies. The allergenic properties of B. cinerea spores are higher if they are germinated (17), but how often they are present in the air as germinated micro-or macroconidia is not known.…”
Section: Discussionmentioning
confidence: 85%
“…The lack of germinability of microconidia and the importance of exposure to airflow or mechanical handling to cause particle aerosolization may be reasons why, as concluded in a review paper, B. cinerea is not measured to be among the dominating fungi in indoor air (26). The facts that B. cinerea is able to grow on building materials and on many common fruits and vegetables, that it produces microconidia and particles smaller than conidial size, and that relatively many people are allergic to B. cinerea (24,27,30,31) may indicate that exposure to B. cinerea is more common than what has been measured in exposure studies. The allergenic properties of B. cinerea spores are higher if they are germinated (17), but how often they are present in the air as germinated micro-or macroconidia is not known.…”
Section: Discussionmentioning
confidence: 85%
“…Moulds can induce the production of specific IgE antibodies, which are related to severity of asthma [25]. However, the association between moisture damage or mould growth and IgE production is very weak [26]. Therefore, non-IgE-mediated mechanisms are more likely.…”
Section: Discussionmentioning
confidence: 99%
“…For instance, the observed levels of volatile organic compounds in damaged homes are usually considerably lower than the levels that would cause irritation [33]. Given the lack of evidence for IgEmediated sensitisation [1,26] and the low indoor levels of most measured irritants in moisture-damaged buildings [34], it is tempting to speculate that the underlying mechanism involves some, as yet unknown, immunological reactions. Unfortunately, due to the low number of specific IgE results among the controls, the present authors were not able to study the association between moisture damage and development of atopy or the potential effect modification by atopy.…”
Section: Discussionmentioning
confidence: 99%
“…Only a small proportion of exposed people are sensitized to molds. 25 Exposure to moisture damage or mold may cause allergy-like symptoms due to histamine release 4 without measured IgE levels. Repeated irritation in the respiratory tract might lead to long-lasting inflammation and inflammationrelated diseases (eg, asthma).…”
Section: Discussionmentioning
confidence: 99%