Skin rejuvenation by microneedle fractional radiofrequency treatment in Asian skin; Clinical and histological analysis

Seo, Kyu Young; Yoon, Moon Soo; Kim, Dong Hyun; Lee, Hee Jung

doi:10.1002/lsm.22071

Cited by 68 publications

(91 citation statements)

References 17 publications

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“…Clinical studies have demonstrated that fractional RF has significant photorejuvenation effect on the aged skin . So far, the photorejuvenation effect of fractional RF has mainly focused on the activation of fibroblasts and increased collagen production in the dermis.…”

Section: Discussionmentioning

confidence: 99%

Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age‐related epidermal dysfunction

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age‐related epidermal dysfunction

et al. 2015

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“…It has been documented that treatment of the skin with RF microneedling has a rejuvenating effect . Dermal remodeling after RF microneedling was shown to produce new collagen, elastin, and hyaluronic acid .…”

Section: Discussionmentioning

confidence: 99%

An open‐label, single‐site study to evaluate the tolerability, safety, and efficacy of using a novel facial moisturizer for preparation and accelerated healing pre and post a single full‐face radiofrequency microneedling treatment

Zahr¹,

Kononov²,

Sensing

et al. 2018

J of Cosmetic Dermatology

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Summary Background Skincare cosmeceutical products have been shown to address intrinsic and extrinsic skin aging. Radiofrequency (RF) with microneedling is effective and safe in improving skin laxity and texture. Pairing skincare cosmeceutical products pre‐ and post‐procedure is beneficial as it enhances patient results, patient results, patient experience, and reduces patient downtime. Objective To evaluate the tolerability, safety, and efficacy of a multi‐ingredient anti‐aging facial moisturizer when applied pre‐ and post‐procedure consisting of a single RF microneedling treatment. Method Fifteen female patients, aged 37‐60, Fitzpatrick skin types I‐IV, with mild‐to‐moderate wrinkles were included in the study. Patients applied a multi‐ingredient anti‐aging facial moisturizer twice a day (morning and night) two weeks prior to RF microneedling and four weeks post‐RF microneedling (twice a day). At each time point, investigator objective assessment, self‐assessments, and clinical photography were taken. Result There were no adverse events as evaluated by the investigator. For this combined treatment and procedure patient scored comfort as the highest for satisfaction. Tolerability parameters erythema and edema were reported after RF microneedling treatment and were significant compared to the pre‐procedure timepoint. Eighty percent of patients showed an improvement in Glogau Wrinkle Scale, but improvement was not statistically significant between baseline and end of study. Improvements in all skin attributes (radiance, tone, smoothness, texture, redness, dryness, and overall appearance) were statistically significant at the end of the study. Self‐perceived skin attribute improvements included overall improvement, brightness, texture, pigmentation, redness, and tightness. The combination of the anti‐aging facial moisturizer and RF microneedling was recommended by the patients in this study. Conclusion This clinical study positively supports the hypothesis that combining the multi‐ingredient anti‐aging facial moisturizer pre‐ and post‐RF microneedling was safe and tolerable for the patients.

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“…The authors concluded that microneedle fractional bipolar RF treatment is effective for the treatment of photoaged Asian faces with darker skin types, and has little risk of postinflammatory hyperpigmentation. The main limitations of this study were the small number of patients and lack of long-term follow-up after the final treatment [8].…”

Section: Scarlet Platformmentioning

confidence: 97%

“…In another study, Seo et al [8] used a microneedle FRF device (Scarlet, Viol Co.) in 25 female patients, evaluating its safety and efficacy for the treatment of skin rejuvenation. In this study, patients received a total of 3 FRF treatments spaced 4 weeks apart.…”

Section: Scarlet Platformmentioning

confidence: 99%

Minimally Invasive Radiofrequency

Mulholland¹,

Halachmi²

2014

Radiofrequency in Cosmetic Dermatology

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Minimally invasive radiofrequency is most commonly applied in a fractional manner (fractional radiofrequency, or FRF). The approach relies on introduction of a set of fine needle electrodes into the skin, which are then activated to deliver energy. Its role is similar to that of fractional lasers, namely to induce neocollagenesis by thermal effects within the dermis. The fractional thermal injury of deep dermal collagen induces a vigorous wound healing process with dermal remodeling and the generation of new collagen, elastin and hyaluronic acid. The major benefit of minimally invasive FRF is that, depending on the needle configuration and insulation, energy can be deposited directly within the dermis with no thermal effects to the epidermis. Side effects are minimal and typically include transient erythema lasting approximately 2 days. It is a viable nonsurgical therapeutic option for the improvement of numerous cosmetic indications including skin rejuvenation, facial skin laxity, rhytides, acne scars, large pores, and photoaged skin. © 2015 S. Karger AG, BaselLaser light and radiofrequency (RF) energy sources have succeeded in effectively treating the typical signs of skin aging. Nonsurgical devices have become very popular in the treatment of rhytides and skin laxity as patients prefer to achieve aesthetic improvement of these cosmetic indications with minimal side effects and downtime.A novel 'minimally invasive RF' approach employing a bipolar microneedle electrode system was recently introduced and its thermal effects on human skin in vivo were characterized in some studies.To improve the efficacy and predictability of nonsurgical treatments, a minimally invasive bipolar RF system was developed with real-time tissue temperature feedback that delivers fractional RF (FRF) thermal pulses to the reticular dermis. This system safely creates thermal injury zones in a fractional manner within the reticular dermis without damage to the dermal-epidermal junction, epidermis or subcutaneous tissue.

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Skin rejuvenation by microneedle fractional radiofrequency treatment in Asian skin; Clinical and histological analysis

Abstract: Microneedle fractional RF is a safe and effective skin rejuvenation method in Asians.

Cited by 68 publications

References 17 publications

Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age‐related epidermal dysfunction

Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age‐related epidermal dysfunction

An open‐label, single‐site study to evaluate the tolerability, safety, and efficacy of using a novel facial moisturizer for preparation and accelerated healing pre and post a single full‐face radiofrequency microneedling treatment

Minimally Invasive Radiofrequency

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