Skin sebum and skin elasticity: Major influencing factors for facial pores

Abstract

Summary Objective The current research work was initiated to develop anti‐aging phytocosmetic formulation of phytoantioxidant, to evaluate their effect on human skin, and to link R parameters of skin with skin sebum and aging. Methods According to COLIPA, 10 healthy male volunteers, aged between 20 and 30 years, having no skin infection or other hypersensitivity disorders, were included in the study. The effect of formulation was evaluated on skin pores and skin elasticity on cheeks for 90 days at regular interval. Various parameters of visible facial pores were assessed using the Skin VisioFace®, Cutometer®, Elastometer®, and Sebumeter®. These data were compared and correlated to examine the possible relationship between visible facial pores, skin elasticity, and skin sebum. Results From R0 to R9, R0, R5, and R9 were negatively correlated with elasticity while R7 shows a positive correlation with elasticity. R7 parameter of Cutometer® was negatively correlated with facial large pores (r = −0.337, P = 0.033). R9 parameter of Cutometer® was significantly positively correlated with facial large pores (r = 0.54, P = 0.000). Conclusion We could assume that the enhancement of skin elasticity would be the fundamental strategies in the prevention of size and count of visible facial pores (fine and large) by the application of formulation containing natural compounds.

Combined therapy with Endoret‐Gel and plasma rich in growth factors vs Endoret‐Gel alone in the management of facial rejuvenation: A comparative study

“…Sebum decrease could therefore prevent from developing other conditions such as acne, folliculitis, seborrheic dermatitis, and subsequent scarring 23,24 . In fact, recent findings have found a direct correlation between skin elasticity improvement, increased hydration and reduced sebum production as a result of the optimal balance of the hydrolipid film on skin 21,22,25 . This may prevent the development of cutaneous lesions derived from sebum excess and abnormal epithelial desquamation 21 …”

“…Both treatment groups decreased the sebum production at 3 and 6 months. Skin pore number and size reduction, which is an important entrance way of bacteria, has been shown to be related with a decrease of sebum production 21,22 . Sebum decrease could therefore prevent from developing other conditions such as acne, folliculitis, seborrheic dermatitis, and subsequent scarring 23,24 .…”

“…Skin pore number and size reduction, which is an important entrance way of bacteria, has been shown to be related with a decrease of sebum production. 21,22 Sebum decrease could therefore prevent from developing other conditions such as acne, folliculitis, seborrheic dermatitis, and subsequent scarring. 23,24 In fact, recent findings have found a direct correlation between skin elasticity improvement, increased hydration and reduced sebum production as a result of the optimal balance of the hydrolipid film on skin.…”

“…23,24 In fact, recent findings have found a direct correlation between skin elasticity improvement, increased hydration and reduced sebum production as a result of the optimal balance of the hydrolipid film on skin. 21,22,25 This may prevent the development of cutaneous lesions derived from sebum excess and abnormal epithelial desquamation. 21 Both treatments have been previously reported to act as a reservoir of biologically active growth factors that can govern and influence cell fate.…”

“…21,22,25 This may prevent the development of cutaneous lesions derived from sebum excess and abnormal epithelial desquamation. 21 Both treatments have been previously reported to act as a reservoir of biologically active growth factors that can govern and influence cell fate. 12,26 Many of these proteins are involved in skin remodelling and include platelet derived growth factor (PDGF), transforming growth factor-β1 (TGFβ1), epidermal growth factor (EGF), insulin-like growth factor-I (IGF-I), hepatocyte growth factor (HGF), basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF).…”