Skin Staining Following Intravenous Iron Extravasation in a Patient With Chronic Kidney Disease: A Case Report

Shi, Ruolin; Marin, Judith; Beaulieu, Monica

doi:10.1177/20543581231165705

Cited by 4 publications

(1 citation statement)

References 19 publications

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“…All IV iron preparations can cause GI disturbances, headache, hypotension, hypertension, and dizziness. IV iron is also considered a vesicant capable of causing long-term skin staining if extravasation occurs 65,66. As with most vesicants, if extravasation occurs, an attempt should be made to aspirate residual medication through the existing IV catheter, the catheter should be removed, cold pack applied, and the extremity elevated, although these interventions will not prevent skin staining.…”

Section: Introductionmentioning

confidence: 99%

Iron Deficiency Related to Obesity

Clark

2024

Journal of Infusion Nursing

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There is a direct correlation between being overweight and iron deficiency. Physiological changes occur in obese adipose cells that contribute to the development of iron deficiency (ID) and iron deficiency anemia (IDA). These changes disrupt the normal iron metabolic checks and balances. Furthermore, bariatric surgery can lead to long-term ID and IDA. Oral iron supplementation may not be effective for many of these patients. Intravenous iron infusions can significantly increase the quality of life for individuals experiencing this condition but are also associated with potentially serious complications. Adequate knowledge about intravenous (IV) iron administration can greatly increase the safety of this beneficial therapy. This review article explains the relationship between obesity, ID/IDA, bariatric surgery and the safe administration of IV iron.

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Section: Introductionmentioning

confidence: 99%

Iron Deficiency Related to Obesity

Clark

2024

Journal of Infusion Nursing

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Ferric derisomaltose/prednisone/warfarin

2023

Reactions Weekly

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Intravenous iron staining: real-world incidence, preventability, and mitigation tools from a long-term quality improvement project

Canning,

Hillen,

Kashiwagi

et al. 2024

International Journal for Quality in Health Care

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Background Iron deficiency is the leading cause of anaemia worldwide and is increasingly treated with intravenous iron therapy. Staining from intravenous iron therapy is a rare but significant and preventable adverse event. To mitigate patient harm, a health service wide quality improvement project was implemented. This study aimed to determine the real-world impact of a quality improvement project on intravenous staining incidents and preventability. Methods A retrospective chart audit was undertaken for all intravenous iron staining episodes reported in a directorate-wide clinical incident reporting database (RiskMan) between 2016 and 2022. Incidence rates of intravenous iron staining, preventability and stain severity were compared pre and post implementation of a standardised intravenous iron procedure. Results Over seven years, 103 intravenous iron stains were identified, resulting in a staining rate of 0.31 stains per 100 infusions (pre 0.27% and post 0.34%, p=0.25). Implementation of the standardised intravenous iron procedure resulted in improvements in pharmacist review of the medication order (61.8% V 89.7%, p<0.01), use of the statewide IV iron infusion consent form (27.3% V 76.9%, p<0.01) and appropriate cannula site (14.3% V 52.5%, P<0.01). Smaller stain sizes were associated with cessation of the infusion at identification of extravasation (312cm2 V 35cm2) (p = 0.04). Preventability was assigned to 86% of stains. Conclusion The incidence rate of intravenous iron staining in a real-world clinical setting is 0.31%. There was increased compliance with several best practice principles and 86% of stains were preventable. Early identification and intervention of potential staining incidents results in smaller iron stains for patients. Quality improvement tools developed for this project can contribute to patient outcomes internationally.

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Skin Staining Following Intravenous Iron Extravasation in a Patient With Chronic Kidney Disease: A Case Report

Cited by 4 publications

References 19 publications

Iron Deficiency Related to Obesity

Iron Deficiency Related to Obesity

Ferric derisomaltose/prednisone/warfarin

Intravenous iron staining: real-world incidence, preventability, and mitigation tools from a long-term quality improvement project

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