SkIndia Quiz 44: Growing asymptomatic nodule on the ear

Miceli, Alyssa; Church, Ann; Ferrer-Bruker, Sarah

doi:10.4103/idoj.idoj_141_17

Cited by 4 publications

(20 citation statements)

References 8 publications

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“…The lesions are usually small, though they may reach a diameter of several centimeters, and are occasionally associated with paroxysmal pain and tenderness. 1,3 The tumor is mainly located in the head, neck, and ventral aspect of the trunk, and less often in the extremities, as in this case. It is most commonly seen in patients between 15 and 35, though any age group can be affected, 3,5 our patient is a 12-year-old female, making our case report particularly unusual.…”

Section: Discussionmentioning

confidence: 68%

“…Eccrine spiradenoma characteristically presents as a dermal or subcutaneous nodular lesion, with a gray, blue, or purple hue. The lesions are usually small, though they may reach a diameter of several centimeters, and are occasionally associated with paroxysmal pain and tenderness 1,3 . The tumor is mainly located in the head, neck, and ventral aspect of the trunk, and less often in the extremities, as in this case.…”

Section: Discussionmentioning

confidence: 70%

“…It is most commonly seen in patients between 15 and 35, though any age group can be affected, 3,5 our patient is a 12‐year‐old female, making our case report particularly unusual. Various clinical forms have been reported such as multiple linear, zosteriform, blaschkoid, and nevoid forms 1 . Malignant transformation is extremely rare, and it can occur especially in patients older than 50 with long‐standing lesions.…”

Section: Discussionmentioning

confidence: 99%

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Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Habib,

Al‐janabi,

Ahmad

et al. 2023

Clinical Case Reports

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Key Clinical MessageSpiradenoma is a rare benign adnexal tumor arising from eccrine sweat glands. It presents as a painful bluish nodular lesion which occurs rarely over the arms. This case report adds to a case where a recurrent spiradenoma occurred over the arm. The majority of reported cases involve young adults, making our pediatric case particularly unusual. Early diagnosis through excisional biopsy is crucial for optimal management and prevention of recurrence or malignant transformation. Eccrine spiradenoma is an uncommon tumor that should be kept in mind in case of a patient with a painful nodule. More genetic studies are needed for the best understanding of this rare tumor entity.

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Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Habib,

Al‐janabi,

Ahmad

et al. 2023

Clinical Case Reports

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“…They typically present as bluish, painful, solitary nodules on the ventral surfaces of the upper body, though multiple nodules also are reported. 5 Spiradenomas manifest as a central constellation of pale large cells surrounded by small, dark, basaloid cells containing hyperchromatic nuclei. The microscopic appearance of the blue basaloid cells contrasts with the clear cells seen in hidradenoma.…”

Section: Hidradenocarcinomamentioning

confidence: 99%

“…The microscopic appearance of the blue basaloid cells contrasts with the clear cells seen in hidradenoma. 5 Merkel cell carcinoma is a cutaneous neuroendocrine tumor affecting elderly or immunosuppressed individuals. It arises in sun-exposed areas and often is associated with Merkel cell polyomavirus infection.…”

Section: Hidradenocarcinomamentioning

confidence: 99%

Exophytic Tumor on the Buttock

Zhang

Kentosh

2021

Cutis

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A 20-year-old woman with no notable medical history presented to the dermatology clinic with an enlarging mass on the right buttock that had been growing over the course of several years. The mass progressed from a small, mildly tender nodule to a 10×10-cm, hyperpigmented, exophytic tumor. There were no other abnormal findings on physical examination, and the patient denied any systemic symptoms. WHAT'S YOUR DIAGNOSIS? a. cutaneous Crohn disease b. hidradenocarcinoma c. lymphangioma d. Merkel cell carcinoma e. spiradenoma

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A malignant spiradenoma of the forehead: a case report and literature review

Ahmed,

Elzawawi,

AlHammadi

et al. 2024

Oxford Medical Case Reports

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Spiroadenomas, arising from sweat glands, are rare benign skin tumors primarily found as solitary nodules on the head, neck, and trunk. The malignant subtype, Spiradenocarcinoma (MSA), originating from benign spiradenomas, is extremely rare and occurs mainly in individuals over 50. MSA exhibits aggressiveness with higher metastasis rates and lower survival rates. Surgical excision is the standard management, supported by imaging modalities like MRI, CT-scan, and ultrasound. We present a 69-year-old female with a medical history of diabetes, hypertension, and dyslipidemia who presented in 2014 with multiple swellings on the forehead and left arm. Initial excisions revealed capillary hemangioma lesions. Subsequent visits involved the excision of further facial and body lesions, with some identified as intradermal nevi. In 2022, she presented to plastic surgery clinic with forehead swelling. The biopsy showed MSA lesion with involved margins. Thus, subsequent re-excision was carried out. One year later, she came with recurrent forehead swelling. Excision and direct closure of the lesion showed involvement of part of the subcutaneous tissue (fat globule) showing residual/recurrent MSA that is very close to nerve trunks. Malignant Spiradenomas (MSAs) usually arise from benign spiradenomas. Therefore, consideration is given to preemptive removal of these tumors due to their potential evolution. The primary treatment approach involves surgery, with a focus on wide local excision and a minimum margin of 1 cm to diminish the risk of metastasis. Vigilant follow-up is essential to promptly identify any recurrences or spreading. What’s already known about this topic? Malignant spiradenoma is an exceedingly uncommon malignant skin adnexal tumor. The primary approach is surgical, involving wide local excision with a margin of at least 1 cm. What does this report add? Highlights the importance of suspecting these lesions early to avoid local metastasis. Shed light on the importance of follow-up visits to be able to monitor the lesion progression or recurrence after excision.

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SkIndia Quiz 44: Growing asymptomatic nodule on the ear

Cited by 4 publications

References 8 publications

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report

Exophytic Tumor on the Buttock

A malignant spiradenoma of the forehead: a case report and literature review

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