Skrining Fitokimia Senyawa Metabolit Sekunder Ekstrak Metanol Daun Jarak Pagar (Jatropha curcas) dengan GCMS

Surahmaida,; Umarudin,; Rani, Agustin Widia; Dewi, Novicalia Citra

doi:10.53342/pharmasci.v6i1.202

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…Selain senyawa jatrofin pada getah tanaman jarak pagar juga memiliki kandungan tanin, dimana senyawa tanin yang terdapat pada bagian batang dan tangkai daun jarak pagar diketahui memiliki kandungan sebesar 18% [4]. Hasil pengujian dengan menggunakan GCMS menunjukan bahwa ekstrak metanol daun jarak pagar terdapat 28 kandungan senyawa metabolit sekunder yang setelah dianalisis aktivitas biologisnya, beberapa diantaranya memiliki khasiat atau manfaat sebagai antioksidan [5].…”

Section: Pendahuluanunclassified

Standarisasi Parameter Spesifik Ekstrak Etanol Daun Jarak Pagar (Jatropha Curcas L) sebagai Vasorelaxan

Sadik,

Zulfian A. Disi

2023

JSSCR

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Jarak pagar (Jatropha curcas L.) is traditionally used as a medicinal plant and can be used scientifically to treat various diseases based on the scientific results of herbal medicine. This study aims to prove that the ethanol extract of Jarak pagar leaves (Jatropha curcas L.) meets the specific parameters for extract standardization. The ethanol extract of Jarak pagar (Jatropha curcas L.) leaves was obtained by maceration method, and then the extract was observed for specific parameters, which included an organoleptic test, identification of chemical content, determination of water-soluble juice content, and ethanol-soluble juice content, as well as other tests to see the activity of Jatropha curcas as a vasorelaxant using experimental methods. The results and data of specific parameter characteristics show that the extract made has met the requirements of Indonesian Medical Materials, which means that the ethanol extract of Jatropha curcas leaves made has met the standards, and based on activity testing, it is known that Jarak pagar leaves (Jatropha curcas L.) have the same activity as Vasorelaxan.

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Section: Pendahuluanunclassified

Standarisasi Parameter Spesifik Ekstrak Etanol Daun Jarak Pagar (Jatropha Curcas L) sebagai Vasorelaxan

Sadik,

Zulfian A. Disi

2023

JSSCR

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Uji Aktivitas Penghambatan Bakteri Endofit Daun Pepaya (Carica papaya L.) Terhadap Staphylococcus aureus

Faujiah,

Hijriani,

Kurniawan

2023

jsn

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Bakteri endofit merupakan bakteri yang mampu menghasilkan senyawa-senyawa bioaktif yang sama dengan tanaman inangnya, salah satunya senyawa antimikroba. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri bakteri endofit daun pepaya (Carica papaya L) terhadap Staphylococcus aureus, Untuk menentukan daya hambat atau zona hambat bakteri endofit terhadap Staphylococcus aureus. Jenis penelitian adalah eksperimental laboratorium. Pengujian menggunakan metode Difusi sumuran pada media MHA. Dilakukan 5 perlakuan yaitu pada Replikasi 1, 2, 3, Kontrol positif ciprofloxacin, kontrol negative aquadest. Hasil pengujian aktivitas antibakteri dilakukan pada isolat yang telah dimurnikan dengan metode difusi sumuran yang menunjukkan bahwa pada bakteri uji Staphylococcus aureus tidak memiliki aktivitas antibakteri.

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Essential Oil Constituents and Pharmacognostic Evaluation of Java Citronella (Cymbopogon winterianus) stem from Bandung, West Java, Indonesia

Haerussana

Chairunnisa

2022

Open Access Maced J Med Sci

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BACKGROUND: Cymbopogon winterianus essential oil contains citral-derived chemicals with a variety of pharmacological effects, although there has been minimal research on pharmacognostic, phytochemical, and biological aspects. AIM: This research aims to evaluate the pharmacognostic and chemical components of C. winterianus stem essential oil. METHODS: The pharmacognostic studies were carried out in terms of macroscopic, microscopic, water content, water extractive values, ethanol extractive values, and essential oil yield. The oil was extracted by ethanol steam distillation method, the oil composition was analyzed by GC-MS. RESULTS: Cymbopogon winterianus stems are 15-35 cm long and 0.5-2 cm broad, with a rough, stiff, and thin texture, with prominent fibers on the top and bottom surfaces. It has a bitter and slightly spicy taste with a distinctive lemony aroma and was greenish yellow in hue with a blend of purplish-red colors. The upper and lower epidermis was examined under a microscope, which revealed sclerenchyma fibers, trichomes, parenchyma, calcium oxalate (rosette), cortex, stem pith, oil cells, stomata (Gramineae type), trachea (ladder and spiral thickening), and collenchyma. The water content was 7.16±0.72%, the water-soluble extractive value was 12.152±0.003%, the ethanol-soluble extractive value was 12.290 ±0.76%, and the essential oil content was 6.46±0.50%. Essential oil constituents were 6-octen-1-ol, 3,7-dimethyl-, formate; trifluoroacetyl-lavandulol; n-hexadecanoic acid; 9,12-octadecadienoic acid (Z,Z)-; oxacyclotetradecane-2,11-dione, 13-methyl-; palmitic acid vinyl ester; glycidyl palmitate; 9,17-Octadecadienal, (Z)-; glycidyl palmitoleate; 1,4-bis(trimethylsilyl)benzene; and cyclotrisiloxane, hexamethyl-. CONCLUSION: The essential oil constituents and preliminary pharmacognostic evaluation of Cymbopogon winterianus stem can provide useful data for further phytochemical analysis, quality control, and standardization of Cymbopogon winterianus. Citronellyl formate detected as citral derivatives as the main compound in the ethanol steam distillation method.

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Skrining Fitokimia Senyawa Metabolit Sekunder Ekstrak Metanol Daun Jarak Pagar (Jatropha curcas) dengan GCMS

Cited by 3 publications

References 12 publications

Standarisasi Parameter Spesifik Ekstrak Etanol Daun Jarak Pagar (Jatropha Curcas L) sebagai Vasorelaxan

Standarisasi Parameter Spesifik Ekstrak Etanol Daun Jarak Pagar (Jatropha Curcas L) sebagai Vasorelaxan

Uji Aktivitas Penghambatan Bakteri Endofit Daun Pepaya (Carica papaya L.) Terhadap Staphylococcus aureus

Essential Oil Constituents and Pharmacognostic Evaluation of Java Citronella (Cymbopogon winterianus) stem from Bandung, West Java, Indonesia

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