Sleep and meal-time misalignment alters functional connectivity: a pilot resting-state study

Yoncheva, YN; Pizinger, Theresa; Kovtun, Kyle; St‐Onge, Marie‐Pierre

doi:10.1038/ijo.2016.132

Cited by 13 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In adults, late eating, which refers to a delay in the timing of meals (usually the main meal of the day or the last meal, as dinner) is robustly associated with hyper-glycemia [12], impaired glucose tolerance [13] and increased risk of poor cardio-metabolic health [14]. Late eating has also been associated with worse sleep patterns [15] and late bedtimes in adults [16].…”

Section: Introductionmentioning

confidence: 99%

Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children

Martínez-Lozano

Tvarijonaviciute

Ríos³

et al. 2020

Nutrients

View full text Add to dashboard Cite

Late eating has been shown to promote metabolic dysregulation and to be associated with obesity in adults. However, few studies have explored this association in children. We compared the presence of obesity, metabolic alterations and circadian-related disturbances between school-aged children who were early dinner eaters (EDE) or late dinner eaters (LDE). School-age children (n = 397; 8–12 years; mean BMI (range): 19.4 kg/m2 (11.6–35.1); 39% overweight/obesity) from Spain were classified into EDE and LDE, according to dinner timing (Median: 21:07). Seven-day-dietary-records were used to assess food-timing and composition. Non-invasive tools were used to collect metabolic biomarkers (saliva), sleep and circadian-related variables (body-temperature and actigraphy). Compared to EDE, LDE were less likely to be overweight/obese [OR: 2.1 (CI: 1.33, 3.31); p = 0.002], and had higher waist-circumference and inflammatory markers, such as IL-6 (1.6-fold) (p = 0.036)) and CRP (1.4-fold) than EDE (p = 0.009). LDE had alterations in the daily patterns of: (a) body-temperature, with a phase delay of 26 min (p = 0.002), and a reduced amplitude (LDE = 0.028 (0.001) and EDE = 0.030 (0.001) (Mean (SEM); p = 0.039); (b) cortisol, with a reduced amplitude (LDE = 0.94 (0.02) and EDE = 1.00 (0.02); p = 0.035). This study represents a significant step towards the understanding of novel aspects in the timing of food intake in children.

show abstract

Section: Introductionmentioning

confidence: 99%

Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children

Martínez-Lozano

Tvarijonaviciute

Ríos³

et al. 2020

Nutrients

View full text Add to dashboard Cite

show abstract

“…Medical students with regular daily meal habits have the highest sleep quality (PSQI: 5.25 ± 2.58) and quality of life (MCS: 77.39 ± 10.46; PCS: 88.21 ± 11.75). Eating irregular meals, especially too many times at night, may cause the peristalsis in the nervous system of the stomach to transmit to the brain, resulting in sleep disturbances such as dreaminess and insomnia [30]. A few low-calorie meals will also disrupt gut microbiota, like long-term fasting, destroying microbiota resistance and colonies recognized by the cerebral cortex and decreasing sleep quality [31][32][33][34][35].…”

Section: Discussionmentioning

confidence: 99%

Multiple mechanisms of action and diet as impossible influencing factors on quality of life and sleep among medical students: a cross-section study

Xue

Wang

Liu

et al. 2023

Preprint

View full text Add to dashboard Cite

Introduction: The ratio of poor sleep quality and life is one of the most common complaints among college students, and medical students had a higher ratio than ordinary college students. However, research on sleep quality and living among Inner Mongolian medical students was scarce. The primary goals of this study were to look into the incidence of sleep and life symptoms and many methods of action and diet involved in medical students of Inner Mongolia in China. Methods A cross-sectional study was done on 1181 university students, ages 16 to 27. They were evaluated using an anonymous, self-administered questionnaire and demographic factors from the Pittsburgh Sleep Quality Index (PSQI) questionnaire and the 36-item Short Form Health Survey (SF-36). The questionnaire was assessed using Cronbach’s alpha coefficient, Kaiser-Meyer-Olkin (KMO), and Bartlett's sphericity. Sleep quality and life disorders, which include demographic and behavioral information, were assessed using the t-test and one-way ANOVA. Also, statistically significant components (P < 0.05) were used for multiple linear regressions progressively fitted to sleep quality and life predictors. SPSS 26.0 software was used for statistical data analysis, P < 0.05 being significantly different. Results One thousand one hundred eighty-one students completed the questionnaire. The incidence of poor sleep quality was 20.7%, whereas life symptoms were for physical PCS and mental MCS summary measures of 1.7% and 3.3% among medical students. The mean ± standard deviation sleep quality and life scores were 5.54 ± 2.64 and 76.65 ± 10.90, 87.23 ± 11.00, respectively. The specific contributions of these two reliable and valid scales (PCS and MCS) were 62.06% and 62.12%. The results revealed that gender, family history of cardiovascular disease, profession, grade, the daily meal taken at a fixed time, grade, eating habits, specific exercise forms, number of daily meals, and intake of other snacks were found to influence PSQI score (P < 0.05). And the factors that influenced the PCS and MCS dimensions of the SF-36 were profession, grades, age, number of daily meals, if there was a fixed daily meal, eating habits, and specific exercises. The results also showed that “the average number of daily meals,” “daily intake of other snacks,” “if there was a fixed daily meal,” “specific exercise forms,” and “family history of cardiovascular disease” were independent influencing factors of PSQI total score. The results of the two portions of SF-36 revealed that “grade,” “average number of daily meals,” “if there was a fixed daily meal,” and “specific exercise forms” influenced on PCS dimension score. “The number of daily meals,” “daily eating habits,” and “specific exercise forms” all had an impact on MCS dimensions score. Conclusions The present research findings revealed a high prevalence of poor sleep quality and life issues among the proposed medical students. The country should implement a tailored intervention for particular risk variables identified to enhance sleep quality and health well-being among university students as they confront unclear future problems.

show abstract

“… 20 Misalignments of sleep and mealtimes affect the functional connectivity of the amygdala in the resting state. 21 Therefore, it is possible that the irregularity of mealtimes is associated with psychosomatic dysfunctions and subsequent presenteeism; however, to our knowledge, there are no reports in the literature to date that refer to the association between mealtime irregularities and presenteeism.…”

Section: Introductionmentioning

confidence: 99%

Psychosomatic Stress Responses and Sleep Disturbance Mediate the Effects of Irregular Mealtimes on Presenteeism

Hayashida¹,

Shimura²,

Higashiyama³

et al. 2021

NDT

View full text Add to dashboard Cite

Background Presenteeism is the loss of work productivity of workers owing to physical and mental problems, and its socioeconomic effects are greater than those of absenteeism. Presenteeism is caused by psychological and physical dysfunctions. On the other hand, the regularity of mealtimes is an important factor associated with physical and mental health conditions. We hence assessed the association among the irregularity of mealtimes, presenteeism, psychological and physical stress responses, and sleep disturbance in office workers in companies. Methods From May to December 2017, the data of 2905 participants who had given their consent to use their information for academic purposes, and answered a questionnaire about the survey and their lifestyle were collected. Path analysis was performed to analyze the association between the irregularity of mealtimes, psychosomatic symptoms (Brief Job Stress Questionnaire), sleep disturbance (Pittsburgh Sleep Questionnaire), and presenteeism (Work Limitations Questionnaire). Results The direct effect of the irregularity of mealtimes on presenteeism was significant but weak. However, the irregularity of mealtimes had a strong effect on presenteeism indirectly through psychological and physical stress responses and sleep disturbance. Conclusion Psychological and physical stress responses and sleep disturbance were identified as mediating factors of the effects of irregularity of mealtimes on presenteeism.

show abstract

Sleep and meal-time misalignment alters functional connectivity: a pilot resting-state study

Cited by 13 publications

References 21 publications

Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children

Late Eating Is Associated with Obesity, Inflammatory Markers and Circadian-Related Disturbances in School-Aged Children

Multiple mechanisms of action and diet as impossible influencing factors on quality of life and sleep among medical students: a cross-section study

Psychosomatic Stress Responses and Sleep Disturbance Mediate the Effects of Irregular Mealtimes on Presenteeism

Contact Info

Product

Resources

About