Sleep architecture and sleep continuity in healthy twins

Frieß, Elisabeth; Ambrosius, U.; Lietzenmayer, S.; Wichniak, Adam; Winkelmann, Juliane; Yassouridis, Alexander; Holsboer, Florian

doi:10.1055/s-2005-918683

Cited by 1 publication

(2 citation statements)

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“…For example, resemblance in alpha rhythms during waking was observed within MZ but not DZ twin pairs [17,18]. Recently, quantitative electroencephalogram (EEG) measures revealed that spectral profiles during non-REM sleep were almost identical in respective DZ twin pairs and also in separated MZ twins who were raised under different environmental conditions [19] (Fig. 1).…”

Section: Genetic Influence On Normal Sleep and Sleep-wake Regulationmentioning

confidence: 98%

“…In the case of insomnia, familial occurrence is common [21]. Although not every sibling in an affected family experiences insomniac symptoms, individuals in a family with and without insomnia would show very similar power spectral distribution in their EEG [19]. Therefore, genetic vulnerability to insomnia would be hidden even in normal sleep cycles, and the signs for potential sleep problems could be assessed by polysomnography.…”

Section: Genetic Influence On Normal Sleep and Sleep-wake Regulationmentioning

confidence: 98%

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Genetics of sleep and sleep disorders

Kimura

Winkelmann

2007

Cell. Mol. Life Sci.

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Genetic factors affect sleep. Studies in twin pairs demonstrate that the strong hereditary influences on sleep architecture and some sleep disorders are transmitted through families. Evidence like this strongly suggests that sleep regulation receives significant influence from genetic factors. Although recent molecular technologies have revealed evidence that genetic traits or gene products trigger particular changes in sleep electroencephalogram activity, we are still far from finding candidate genes or multiple mutations responsible for individual sleep disorders. Sleep is a very complex phenotype. Genetic susceptibility and environmental factors should be also considered as contributors to sleep phenotype. The aim of this review is to present a current summary and future prospects for genetic studies on sleep and selected sleep-associated disorders.

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Section: Genetic Influence On Normal Sleep and Sleep-wake Regulationmentioning

confidence: 98%

Section: Genetic Influence On Normal Sleep and Sleep-wake Regulationmentioning

confidence: 98%