Sleep disordered breathing (SDB) in neonates and implications for its long-term impact

Mehta, Bhavesh; Waters, Karen A.; Fitzgerald, Dominic A.; Badawi, Nadia

doi:10.1016/j.prrv.2019.10.003

Cited by 9 publications

(12 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Preterm infants are at elevated risk for any number of sleep problems during childhood and adulthood 69 . Since sleep is essential to health, particularly for development, metabolism, immune system, memory, and learning of infants and children, the adverse effects of prematurity on paediatric sleep may be significant and under‐appreciated 11 …”

Section: Commentmentioning

confidence: 99%

“…Since neonates preferentially breathe through their nose and have high nasal resistance, even relatively mild nasal congestion or obstruction can result in respiratory problems. Moreover, the inherent complexity of a highly compliant chest wall, relatively stiff lung and dependence on rapid breathing in the neonate can readily lead to desaturation when there is upper airway obstruction 11 . It should be noted that sleep‐disordered breathing occurs in both term and preterm neonates and can be challenging to study quantitatively.…”

Section: Commentmentioning

confidence: 99%

“…Study of AOP is challenged by a lack of expert consensus on terminology used to describe the condition. 1,2,[10][11][12][13][14] As terminology evolves and continues to be defined, there are instances where studies and descriptions of AOP may at times be measuring different clinical entities.…”

Section: Commentmentioning

confidence: 99%

“…69 Since sleep is essential to health, particularly for development, metabolism, immune system, memory, and learning of infants and children, the adverse effects of prematurity on paediatric sleep may be significant and under-appreciated. 11 Sleep-disordered breathing may occur in both full-term and preterm neonates. Since neonates preferentially breathe through their nose and have high nasal resistance, even relatively mild nasal congestion or obstruction can result in respiratory problems.…”

Section: Sleep Disorders Later In Lifementioning

confidence: 99%

See 3 more Smart Citations

The epidemiology of apnoea of prematurity

Pergolizzi

Fort

Miller

et al. 2022

Clinical Pharmacy Therapeu

View full text Add to dashboard Cite

Apnoea of prematurity (AOP) does not have a precise definition, but is generally applied when a premature infant displays cessation of respiration for 20 or more seconds or less than 20 s if accompanied by cyanosis, pale colour of the skin or bradycardia (<100 beats per minute). 1 Another term that is occasionally used is apnoea and bradycardia of prematurity (ABP). We use the abbreviation AOP here for both terms. This is defined as cessation of breathing for ≥20 s accompanied by bradycardia, defined as <100 beats per minute. AOP occurs with preterm delivery, generally in an inverse relationship with gestational age (GA). Preterm birth, defined as delivery at age less than 37 weeks' gestation, is a global phenomenon with an incidence between 5% and 18% across 184 countries. 2 Approximately 15 million infants per year are born prematurely according to the World Health Organization (WHO), 3 representing a substantial

show abstract

Section: Commentmentioning

confidence: 99%

Section: Commentmentioning

confidence: 99%

Section: Commentmentioning

confidence: 99%

Section: Sleep Disorders Later In Lifementioning

confidence: 99%

See 2 more Smart Citations

The epidemiology of apnoea of prematurity

Pergolizzi

Fort

Miller

et al. 2022

Clinical Pharmacy Therapeu

View full text Add to dashboard Cite

show abstract

“…8 Obstructive sleep apnea is an important cause of nocturnal enuresis in children and should be considered in the differential diagnosis of nocturia. 92,93 Malignancy. There is recent epidemiological data suggesting that OSA is carcinogenic, the potential existence of severe OSA and cancer has gained increasing attention in the last decade.…”

Section: Measurementmentioning

confidence: 99%

Diagnosis and management of childhood sleep-disordered breathing

Al-Shamrani

Alharbi‎

2020

SMJ

View full text Add to dashboard Cite

Sleep-disordered breathing (SDB) includes disorders of breathing that affect airway patency, which impair children's sleep and lead to negative consequences. Obstructive sleep apnea, hypoventilation and upper airway resistance syndrome are common causes of morbidity and mortality in childhood. These clinical practice guidelines, intended for use by pediatricians and primary care clinicians, provide a clear recommendation for the diagnosis and management of sleep-disordered breathing, focusing on the most serious disorder, obstructive sleep apnea syndrome (OSAS). These clinical guidelines formulate clear recommendations to identify patients with suspected OSAS. Further, the manuscript will highlight the potential consequences of SBD in children, and how to overcome such difficulties, what could be the therapeutic options, a 12 recommendations and what are the future direction for pediatric sleep medicine.

show abstract

Obstructive sleep apnea in young infants: Sleep position dependence and spontaneous improvement

Kukkola

Kirjavainen

2022

Pediatric Pulmonology

View full text Add to dashboard Cite

Objectives The natural evolution of obstructive sleep apnea (OSA) in young infants is not established. Methods We re‐evaluated 10‐year pediatric sleep center infant polysomnography (PSG) data, excluding infants with syndromes, genetic defects, structural anomalies or periodic breathing > 5% of sleep time. Results Obstructive events > 1 h‐1 were evident in 255 infants, of which 91 were eligible for the study. Of the 38 infants in a follow‐up study, 30 (79%) were male, 15 (40%) were born prematurely, 25 (66%) had observed apneas, and 13 (33%) had experienced a brief, unexplained event or had a sibling of the infant died suddenly. The first PSG was performed at a median corrected age of 4 weeks (interquartile range [IQR] 2−7) and the second at 11 weeks (IQR 9−14). The obstructive apnea and hypopnea index (OAHI) was greater in the supine compared to side‐sleeping position in both recordings (p < 0.001), whereas OAHI dropped from 10 h‐1 (IQR 6−24) in the first PSG to 3 h‐1 (IQR 1−9) in the second PSG (p < 0.001). OSA alleviation was also observable as a decrease in the number of oxygen desaturations (p < 0.001), as a decrease in transcutaneous (p = 0.001) and end‐tidal carbon dioxide (p = 0.01) 95th percentile levels, and work of breathing (p = 0.002). Seven infants had a third PSG to verify a satisfactory improvement of OSA. Conclusions OSA in young infants without a clear syndrome or structural anomaly is sleep position dependent and shows improvement during the following few months.

show abstract

Sleep disordered breathing (SDB) in neonates and implications for its long-term impact

Cited by 9 publications

References 78 publications

The epidemiology of apnoea of prematurity

The epidemiology of apnoea of prematurity

Diagnosis and management of childhood sleep-disordered breathing

Obstructive sleep apnea in young infants: Sleep position dependence and spontaneous improvement

Contact Info

Product

Resources

About