Sleep Disorders and Fibromyalgia

Roizenblatt, Suely; Neto, Nilton Salles Rosa; Tufik, Sérgio

doi:10.1007/s11916-011-0213-3

Cited by 80 publications

(50 citation statements)

References 90 publications

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“…It has been suggested that in FMS, increased sympathetic activity in CNS and release of proinflammatory cytokines from glial cells adversely affects sleep quality. On the other hand, sleep has been suggested to have an impact on fibromyalgia symptoms, with an underlying immunological pathogenesis, and effects of mediator cytokines, such as TNF-α and IL1-β, involved in the sleep regulating regions of CNS on the the emergence of FMS symptoms have also been indicated [23]. In our study, complaints of sleep disorders were found in similar patients with FMS and OSAS.…”

Section: Discussionsupporting

confidence: 62%

“…Patients with AHI of ≥5 events/h were diagnosed with OSAS. Based on their AHI scores, the patients were categorized into mild (AHI, 5-15), moderate (AHI, [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30], and severe OSAS (AHI, >30) groups according to the AASM Task Force criteria [11]. Oxygen desaturation index (ODI) was defined as the total number of measurements of oxyhemoglobin desaturation of ≥4% within ≥10 s-<3 min from the baseline divided by the total sleep time.…”

Section: Psg Evaluationmentioning

confidence: 99%

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Is There a Link Between Obstructive Sleep Apnea Syndrome and Fibromyalgia Syndrome?

et al. 2017

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OBJECTIVES:Fibromyalgia syndrome (FMS) is characterized by complaints of chronic musculoskeletal pain, fatigue, and difficulty in falling asleep. Obstructive sleep apnea syndrome (OSAS) is associated with symptoms, such as morning fatigueness and unrefreshing sleep. We aimed to investigate the presence of OSAS and objectively demonstrate changes in sleep pattern in patients with FMS. MATERIAL AND METHODS:Polysomnographic investigations were performed on 24 patients with FMS. Patients were divided into two groups: patients with and without OSAS (Group 1 and Group 2, respectively). A total of 40 patients without FMS who presented to the sleep disorders polyclinic with an initial diagnosis of OSAS were included in Group 3. Based on their apnea hypopnea index (AHI), OSAS in the patients were categorized as mild (AHI,(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15), moderate (30), or severe (>30). RESULTS:OSAS was detected in 50% of patients with FMS. The most prominent clinical findings were morning fatigue and sleep disorder, which were similar in three groups. In polysomnography (PSG) evaluation, patients with FMS had mild (33%), moderate (25%), and severe (42%) OSAS. In correlation analyses, negative correlations were observed between fibromyalgia impact questionnaire (FIQ) and mean oxygen saturation, visual analogue scale (VAS), and minimum oxygen saturation, whereas a positive correlation was found between FIQ and desaturation times in patients with FMS. CONCLUSION:Detection of OSAS in 50% of the patients with FMS, and similar rates of complaints of sleep disorder and morning fatigue of OSAS and FMS cases are important results. Detection of correlation between the severity of hypoxemia and FIQ and VAS scores are significant because it signifies the contribution of increased tissue hypoxemia to the deterioration of clinical status. Diagnosis and treatment of OSAS associated with FMS are important because of their favorable contributions to the improvement of the clinical picture of FMS. KEYWORDS:Obstructive sleep apnea syndrome, fibromyalgia syndrome, polysomnography, sleep disorders, apnea hypopnea index, hypoxemia INTRODUCTIONFibromyalgia syndrome (FMS) is a chronic health problem that presents with pain all over the body, with other symptoms, such as tenderness of the affected joints, muscles fatigue, sleep problems (waking up unrefreshed and excessive daytime sleepiness), and cognitive impairment [1]. Since its etiology is not fully known, its treatment is symptomatic. Patients with FMS are usually treated with various combinations of physiotherapy, psychotherapy, psychotrophic drugs, and analgesics. Treatment effectiveness in FMS is limited, and these patients frequently lead their lives with symptoms of chronic insomnia, sleep problems, fatigue, and pain [2].Obstructive sleep apnea syndrome (OSAS) is a pathology with systemic effects that are characterized by associated symptoms of recurrent episodes of upper respiratory tract obstruction, hypoxemia, arousals during sleep, morning fatigue because of impaired sleep ...

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Section: Discussionsupporting

confidence: 62%

Section: Psg Evaluationmentioning

confidence: 99%

Is There a Link Between Obstructive Sleep Apnea Syndrome and Fibromyalgia Syndrome?

et al. 2017

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“…Sleep disorders like obstructive sleep apnea and restless legs syndrome appear to be more common in patients with FMS, particularly in male patients, than in the general population [151][152][153][154][155][156], and FMS may be more prevalent among patients with sleep apnea than in the general population [157]. The presence of such sleep disorders is associated not only with worse perceived sleep quality, but also with pain, fatigue, and greater symptoms severity (assessed with the Fibromyalgia Impact Questionnaire, FIQ) [151,156].…”

Section: Sleepmentioning

confidence: 96%

Fibromyalgia: A Critical and Comprehensive Review

Borchers

Gershwin

2015

Clinic Rev Allerg Immunol

229

217

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Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise classification. It is often considered as part of the global overview of functional somatic syndromes that are otherwise medically unexplained or part of a somatization disorder. Patients with fibromyalgia share symptoms with other functional somatic problems, including issues of myalgias, arthralgias, fatigue and sleep disturbances. Indeed, there is often diagnostic and classification overlap for the case definitions of a variety of somatization disorders. Fibromyalgia, however, is a critically important syndrome for physicians and scientists to be aware of. Patients should be taken very seriously and provided optimal care. Although inflammatory, infectious, and autoimmune disorders have all been ascribed to be etiological events in the development of fibromyalgia, there is very little data to support such a thesis. Many of these disorders are associated with depression and anxiety and may even be part of what has been sometimes called affected spectrum disorders. There is no evidence that physical trauma, i.e., automobile accidents, is associated with the development or exacerbation of fibromyalgia. Treatment should be placed on education, patient support, physical therapy, nutrition, and exercise, including the use of drugs that are approved for the treatment of fibromyalgia. Treatment should not include opiates and patients should not become poly pharmacies in which the treatment itself can lead to significant morbidities. Patients with fibromyalgia are living and not dying of this disorder and positive outlooks and family support are key elements in the management of patients.

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“…It is essential to incorporate sleep medicine in the core curriculum of any perioperative fellowship program because it has relevance in multiple areas of anesthesia, such as out-of-OR sedation, perioperative airway management with positive airway pressure techniques, and as a comorbidity in the management of pain-related disorders. 42,61 With respect to other respiratory conditions, cigarette smoking continues to be prevalent in the surgical population. Effective preoperative counselling on smoking cessation is not emphasized in residency curricula.…”

Section: Discussionmentioning

confidence: 99%

Perioperative fellowship curricula in anesthesiology: a systematic review

Gharapetian

Chung

Wong

et al. 2014

Can J Anesth/J Can Anesth

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Purpose Perioperative medicine is emerging as a unique area of medical practice. Anesthesiology graduates are particularly well suited for this role given their training. The purpose of this systematic review is to summarize the various fellowships being offered in perioperative medicine and the scope of clinical perioperative practice that currently exists. The common areas of competency covered in these perioperative medicine fellowships are also identified.

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Sleep Disorders and Fibromyalgia

Cited by 80 publications

References 90 publications

Is There a Link Between Obstructive Sleep Apnea Syndrome and Fibromyalgia Syndrome?

Is There a Link Between Obstructive Sleep Apnea Syndrome and Fibromyalgia Syndrome?

Fibromyalgia: A Critical and Comprehensive Review

Perioperative fellowship curricula in anesthesiology: a systematic review

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