Sleep Disorders and Restless Legs Syndrome in Hemodialysis Patients in Greece: A Cross-Sectional Study

Stergiannis, Pantelis; Govari, Maria; Jahaj, Edison; Marvaki, Christina; Toulia, Georgia; Marvaki, Katerina; Chasioti, Georgia; Intas, George

doi:10.1007/978-3-030-32633-3_21

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…Neurological features and sleep disorders are most prevalent in RLS, resulting in interrupting patients’ life activities; a recent cross-sectional study stated a significant association between insomnia and RLS. The study also showed that the RLS was significantly tied to hypnotics 16. They have a considerable impact on patients’ quality of life and their adherence to medical care.…”

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confidence: 77%

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Restless Leg Syndrome in Hemodialysis Patients

et al. 2022

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Background: Restless legs syndrome (RLS) is a clinical entity characterized by sensory-motor manifestations commonly observed in end-stage renal illness. Evidence suggests that RLS is a multifactorial phenomenon that can be influenced by many critical factors, including genetic predisposition, dietary patterns, and deficiency in some vitamins. Iron metabolism disorders and metabolic derangements have been generally accepted as predisposing elements in RLS. Furthermore, both pharmacological and neuroimaging studies demonstrated dopamine deficiency and dopamine receptors decrease in basal ganglia during RLS.

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confidence: 77%

“…The study also showed that the RLS was significantly tied to hypnotics. 16 They have a considerable impact on patients' quality of life and their adherence to medical care. Furthermore, hemodialysis patients with RLS face an increased risk of muscle atrophy and weakness.…”

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confidence: 99%

Restless Leg Syndrome in Hemodialysis Patients

et al. 2022

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“…However, patients on HD are more vulnerable to RLS due to ferritin loss and changes in phosphate and parathyroid hormone levels, suggesting that HD is a significant risk factor for RLS (Huzmeli et al., 2018; Ramachandran et al., 2018). Moreover, HD ‐related RLS is associated with a variety of physical and psychological disorders, such as insomnia, fatigue, anxiety, and depression, which seriously affect patients’ prognosis and quality of life and even lead to an increased risk of cardiovascular events and death (Mousavi et al., 2021; Stergiannis et al., 2020; Tuncel et al., 2011, 2019; Tsai et al., 2019; Yang et al., 2019; Zhang et al., 2020).…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, HD -related RLS is associated with a variety of physical and psychological disorders, such as insomnia, fatigue, anxiety, and depression, which seriously affect patients' prognosis and quality of life and even lead to an increased risk of cardiovascular events and death (Mousavi et al, 2021;Stergiannis et al, 2020;Tuncel et al, 2011Tuncel et al, , 2019Tsai et al, 2019;Yang et al, 2019;Zhang et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Global prevalence of restless legs syndrome among hemodialysis patients: A systematic review and meta‐analysis

Zhou,

Liu,

Zhang

et al. 2024

Brain and Behavior

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Objectives: Restless legs syndrome (RLS) is a common complaint in patients undergoing hemodialysis (HD). Despite the fact that the estimated prevalence of RLS among HD patients is widely reported, these results varied significantly in the relevant literature. Due to this limitation, the aim of this study was to determine the global prevalence of RLS among HD patients.Methods: This systematic review was conducted and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐analyses 2020 statement. We searched the electronic databases: Cochrane Library, PubMed, Embase, Web of Science, Scopus, Cumulative Index to Nursing and Allied Health Literature, China Knowledge Resource Integrated Database, Wanfang Database, Chinese Biomedical Database, and Weipu Database. A random effects model was employed to calculate pooled prevalence rates.Results: The global pooled prevalence of RLS in HD patients was 27.2% (95% CI: 24.8–29.7). Stratified analyses demonstrated that included studies with sample size <100 had the highest pooled prevalence of RLS. The prevalence of RLS using clinical interviews and questionnaires was 28.7% (95% CI: 25.2–32.2) and 25.9% (95% CI: 22.8–29.1), respectively. RLS prevalence is higher in females (29.7%, 95% CI: 26.2–33.2) HD patients than in males (23.5%, 95% CI: 20.9–26.0), and the African region has the highest prevalence in the world when the diagnostic criteria were restricted to the 2003 version of International RLS Study Group criteria, the prevalence of RLS was highest (28.9%, 95% CI: 25.9–31.9).Conclusion: Our results revealed a high RLS prevalence in HD patients worldwide. However, the prevalence of RLS among HD patients varied significantly based on sample size, data collection method, gender, diagnostic criteria, and geographical region.

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Prevalence and risk factors of poor sleep quality in continuous ambulatory peritoneal dialysis patients in Nanchang, Southeast China

et al. 2022

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This study aimed to explore the prevalence and risk factors of poor sleep quality in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) at the peritoneal dialysis center of the First Affiliated Hospital of Nanchang University. This cross-sectional study was conducted from March 2019 to December 2019. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the sleep quality of patients undergoing CAPD. A PSQI score of ≥5 was defined as poor sleep quality, whereas a PSQI of <5 was defined as good sleep quality. Logistic regression analysis was used to analyze risk factors for poor sleep quality. In total, 456 patients undergoing CAPD were investigated. The average PSQI score was 5.0 ± 2.9. Among the participants, 46.3% had poor sleep quality, and 45.6% were female patients. The average age was 49.4 ± 13.3 years. Compared with good sleepers, poor sleepers included a higher proportion of females and calcium–phosphorus (Ca × P) product, longer dialysis durations, lower total endogenous creatinine clearance rates, less residual renal function, and lower albumin levels. Multivariate logistic regression analysis showed that a long dialysis duration, low albumin level, and high Ca × P product were independent risk factors for poor sleep quality in patients undergoing CAPD. Odds ratios (95% confidence interval) for these risk factors were 1.01 (1.00–1.02), 0.95 (0.91–1.00), and 1.02 (1.00–1.03), respectively. Interventions aimed at improving albumin and Ca × P product levels may improve quality of life for CAPD patients.

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Sleep Disorders and Restless Legs Syndrome in Hemodialysis Patients in Greece: A Cross-Sectional Study

Cited by 4 publications

References 16 publications

Restless Leg Syndrome in Hemodialysis Patients

Restless Leg Syndrome in Hemodialysis Patients

Global prevalence of restless legs syndrome among hemodialysis patients: A systematic review and meta‐analysis

Prevalence and risk factors of poor sleep quality in continuous ambulatory peritoneal dialysis patients in Nanchang, Southeast China

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