Sleep Disorders in Childhood Epileptic Disorders

Abstract

Sleep disorders are common in children, especially in children with epileptic disorders. This article reviewed most recent publications supporting a reciprocal relationship between sleep disorders and childhood epileptic disorders as well as the underlying mechanisms involved in both disease processes, i.e. similar neuronal networks in the genesis of sleep and epileptic seizures. Evidence support that sleep disorders can aggravate Interictal Epileptiform Discharges (IEDs) and nocturnal seizures in children with epilepsy, leading to poor seizure control and increasing functional disturbance in patients with childhood epileptic disorders; On the other hand, childhood epileptic disorders and some antiepileptic medications and vagus nerve stimulator can change sleep quality and architecture of sleep, resulting in an increase in troubled sleep, which can lead to increased sleep disorders. Recognizing and effectively treating sleep disorders in patients with childhood epileptic disorders can improve seizure control and overall functioning and vice versa.

Therapeutic potential of hypnotic herbal medicines: A comprehensive review

“…Sleep disorders have complicated and multiple underlying mechanisms that involve a variety of physiological, psychological, and environmental components (Liu et al, 2018). Additionally, lifestyle factors such as stress, diet, and physical activity can contribute to sleep disorders.…”