Sleep duration and mortality: a systematic review and meta‐analysis

Abstract

Epidemiologic studies have shown that sleep duration is associated with overall mortality. We conducted a systematic review of the associations between sleep duration and all-cause and cause-specific mortality. PubMed was systematically searched up to January, 2008 to identify studies examining the association between sleep duration and mortality (both all-cause and cause-specific) among adults. Data were abstracted serially in a standardized manner by two reviewers and analyzed using random-effects meta-analysis. Twenty-three studies assessing the associations between sleep duration and mortality were identified. All examined sleep duration measured using participant self-report. Among the 16 studies which had similar reference categories and reported sufficient data on short sleep and mortality for meta-analyses, the pooled relative risk (RR) for all-cause mortality for short sleep duration was 1.10 [95% confidence interval (CI): 1.06, 1.15]. For cardiovascular-related and cancer-related mortality, the RRs associated with short sleep were 1.06 (95% CI: 0.94, 1.18) and 0.99 (95% CI: 0.88, 1.13), respectively. Similarly, among the 17 studies reporting data on long sleep duration and mortality, the pooled RRs comparing the long sleepers with medium sleepers were 1.23 (95% CI: 1.17, 1.30) for all-cause mortality, 1.38 (95% CI: 1.13, 1.69) for cardiovascular-related mortality, and 1.21 (95% CI: 1.11, 1.32) for cancer-related mortality. Our findings indicate that both short sleepers and long sleepers are at increased risk of all-cause mortality. Further research using objective measures of sleep duration is needed to fully characterize these associations.

Sleep Duration and Cancer Risk: a Systematic Review and Meta-analysis of Prospective Studies

“…Interestingly, studies have shown that both short sleep duration, defined as sleeping ≤6 h per night, and long sleep duration, defined as sleeping ≥9 h, may be associated with many health outcomes, including total mortality (Gallicchio et al, 2009;Cappuccio et al, 2010b), cardiovascular disease (Ferrie et al, 2007;Meisinger et al, 2007;Ikehara et al, 2009;Stone et al, 2009), type 2 diabetes (Cappuccio et al, 2010a), hypertension (Guo et al, 2013), obesity (Cappuccio et al, 2008;Stranges et al, 2008a) and poor self-rated health (Steptoe et al, 2006), as well as cancers (Yang et al, 2013). Two studies reported a U-shaped association between sleep duration and cancer risk (Jiao et al, 2013;Zhang et al, 2013); whereas other studies did not reveal such an association (Kakizaki et Hao Zhao 1,2,3& , Jie-Yun Yin 2& , Wan-Shui Yang 1 , Qin Qin 2 , Ting-Ting Li 2 , Yun Shi 2 , Qin Deng 1 , Sheng Wei 2 , Li Liu 2 *, Xin Wang 1 *, Shao-Fa Nie 2 * von Ruesten et al, 2012), or only found a null association (Verkasalo et al, 2005;McElroy et al, 2006;Pinheiro et al, 2006;Sturgeon et al, 2012;Luo et al, 2013).…”

Prevalencia de insomnio en adultos de 18-60 años y exposición a campos electromagnéticos en hogares de la ciudad de Barranquilla, Colombia

“…Algunas revisiones sistemáticas señalan que tanto el sueño corto (<7 horas) como el sueño excesivo (>9 horas) se asocian a un mayor riesgo de mortalidad por todas las causas (2,3).…”

Health indicators associated with poor sleep quality among university students

“…Current epidemiological studies have demonstrated that short duration sleep (< 7 hours) is strongly associated with general mortality, principally with cardiovascular diseases (CVD) and type 2 diabetes mellitus (DM 2), in relation to subjects who reported sleeping for more than 8 hours per night (1)(2) . On the other hand, a meta-analysis observed that subjects who sleep for a long time (> 9 hours) and for a short time (< 7 hours) have a life expectancy reduced principally by CVD and cancer, above all in women (2) .…”