Sleep EEG characteristics associated with sleep onset misperception

Abstract

DOI to the publisher's website.• The final author version and the galley proof are versions of the publication after peer review.• The final published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal.If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the "Taverne" license above, please follow below link for the End User Agreement:

Analysis of Clinical Characteristics and Polysomnography Indicators of Obstructive Sleep Apnea–Hypopnea Syndrome Patients Based on Sleep Perception Types

“…We found that there was a negative correlation between sleep perception and the number of spontaneous arousal, which means that the better the sleep perception, the fewer the number of spontaneous arousals. Hermans et al (13) found that the misperception of SL was related to the increase in N1 sleep period and the increase in WASO, which indicates that light sleep and fragmentation of sleep are associated with abnormal sleep perception in individuals. However, our study also found that sleep perception had no correlation with the patient's arousal index.…”

Assessing sleep-wake survival dynamics in relation to sleep quality in a placebo-controlled pharmacological intervention study with people with insomnia and healthy controls

“…(b) Misperception of TST, calculated as the difference between self-reported subjective TST and objectively measured TST between treatment conditions can be explained by predictable alterations of sleep fragmentation at the beginning of the night. Importantly, the model to estimate subjective sleep onset was developed from another night of measurement, partly with the same study participants (Hermans et al 2019). This may explain why the parameter of 30 min seemed to fit so well in the current study.…”

“…We used the previously introduced model to determine whether the difference in sleep onset misperception between the zopiclone night and the placebo night could be attributed to predictable changes in sleep fragmentation or to factors not explained by the model (Hermans et al 2019). In the sleep length model, it was assumed that sleep bouts with a too short length at sleep onset are perceived as wake (Hermans et al 2019). Thus, the perceived sleep onset was estimated as the start of the first sleep fragment longer than L minutes.…”

Mild Obstructive Sleep Apnea Tends to Be Associated with Sleep State Misperception

“…A recent study by Hermans et al [10] using sleep EEG suggested that sleep fragmentation in the early part of the night sleep contributes to the mechanisms of SSM. The proportion of each sleep stage [i.e., N3 stage sleep, rapid eye movement (REM) sleep] is also suggested as an important factor affecting SSM [11][12][13].…”

“…Obstructive sleep apnea (OSA) is a common sleep breathing disorder manifested by increased arousal and sleep fragmentation, which overlap with candidate etiologies of SSM [9,10]. Patients with OSA often experience arousal at the end of apnea and hypopnea, and experience sleep fragmentation due to repetitive respiratory events that disturb deep sleep.…”