Sleepiness Combined with Low Alcohol Intake in Women Drivers: Greater Impairment but Better Perception than Men?

Barrett, P R; Horne, Jim; Reyner, L A

doi:10.1093/sleep/27.6.1057

Cited by 25 publications

(28 citation statements)

References 8 publications

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“…[40] Other studies have found that the combination of alcohol (BAC = .04) and restricted sleep increased lane drifting during simulated driving. [41,42] These studies suggest that lower BACs combined with other impairment sources can have a similar effect on driving as BACs that are above the per se limit. The prevalence of fatal crashes where alcohol and another drug were found underestimates the comorbidity weakness of per se definitions.…”

Section: Figure 4-2 Alcohol and Drug Co-morbiditymentioning

confidence: 94%

Review of Technology to Prevent Alcohol-Impaired Crashes (TOPIC)

Pollard¹,

Nadler²,

Stearns³

2007

PsycEXTRA Dataset

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Section: Figure 4-2 Alcohol and Drug Co-morbiditymentioning

confidence: 94%

Review of Technology to Prevent Alcohol-Impaired Crashes (TOPIC)

Pollard¹,

Nadler²,

Stearns³

2007

PsycEXTRA Dataset

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“…This is described in detail elsewhere (Barrett et al, 2004). Briefly, it comprises an immobile car with an interactive full size computer-generated dull, monotonous roadway.…”

Section: Simulatormentioning

confidence: 99%

“…Increases in alpha and theta power indicate increasing sleepiness (Rechtschaffen and Kales, 1968;Å kerstedt and Gillberg, 1990). The EEG power in this (4-11 Hz) range was averaged per minute, and standardized for each participant using the method described by Barrett et al (2004).…”

Section: Eeg and Eogmentioning

confidence: 99%

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Early evening low alcohol intake also worsens sleepiness‐related driving impairment

Barrett

Horne

Reyner

2005

Human Psychopharmacology

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Following night-time sleep restriction, afternoon driving performance during the bi-circadian surge in afternoon sleepiness is markedly worsened by blood alcohol concentrations (BACs) well under most national driving limits. This study assessed how driving with this same sleep restriction and BACs (av 40 mg and 28 mg alcohol/100 ml blood at the beginning and end of drive, respectively) respond during the evening circadian rise in alertness. In a 2 x 2 (alcohol versus control drink [double blind] x normal night sleep versus sleep restricted), repeated-measures design, eight healthy young men drove for 2 h from 18:00 h, in a real-car simulator, on a monotonous, simulated highway. Driving impairment (lane drifting), subjective sleepiness and EEG measures of sleepiness were recorded. While sleep restriction alone produced significant impairments to evening driving and subjective sleepiness, alcohol alone did not. However, alcohol combined with sleep restriction significantly worsened all indices, although, this was less than that found for afternoon driving with identical interventions. Whereas low BACs may not affect driving in normally alert drivers in the early evening, the addition of moderate sleep restriction still produces a dangerous combination. Probably, there is no 'safe' level of alcohol intake for otherwise sleepy drivers, at any time of the day.

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“…Besides the intake of drugs, sleep deprivation in itself is considered a risk factor for road traffic accidents (Anund 2009;Barrett et al 2004;Biggs et al 2007;Desai et al 2006;Hack et al 2001;Jackson et al 2008;Lenne et al 1998;Orzel-Gryglewska 2010;Philip et al 1999Philip et al , 2004Reynolds and Banks 2010;Vakulin et al 2007). Amphetamine influences the function of the central nervous system by releasing and blocking the reuptake of catecholamines and has been shown to improve cognitive and motor function in sleep-deprived subjects (Magill et al 2003).…”

Section: Introductionmentioning

confidence: 99%