The Hepatitis-B (HBV) epidemic's dynamic can be presented as a compartment model. Determining the HBV epidemic control strategy can be considered a nonlinear feedback control problem. The sliding mode controller (SMC) is an effective feedback control method for controlling the dynamical system under disturbances. Recently, the SMC based on fractional order calculus can provide preferable characteristics for a control system such as robustness and convergence rate. In this study, the HBV epidemic system's control policy is proposed using the fractional order sliding mode controller (FOSMC). The control policy with multiple measures including vaccination, isolation, and treatment is formulated to manipulate the susceptible and the infected subpopulations to the desired level. The Lyapunov-based approach is proven for stability analysis. The control policy is applied to the simulation example to verify the feasibility of the proposed FOSMC method. The simulation results are compared with those of the integer order SMC. By the proposed method, the results reveal that the susceptible and infected subpopulations are driven to the desired levels under disturbances with a higher convergence rate compared to that of the integer one. Moreover, the proposed FOSMC method can reduce the chattering occurrence which is the primary drawback of the SMC method.