Slow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardia

Cardiac purinergic signalling in health and disease

“…Caffeine can also induce PSVT [669]. Slow infusion of calcium channel blockers are claimed to be a safe alternative to adenosine for the emergency treatment of PSVT [671]. The relative efficacy of adenosine and verapamil for the treatment of PSVT were found to be similar; adenosine had a higher rate of minor adverse effects, while verapamil had a higher rate of causing hypotension [672].…”

Diagnosis and management of supraventricular tachycardias

“…Administering a calcium-channel blocker intravenously over 20 minutes has been shown to reduce the rate of hypotension. 23 There are fewer data supporting the use of β-blockers in the acute treatment of SVT; however, they are considered reasonable choices because of their safety profile. 5,23 If all aforementioned pharmacologic therapies fail, synchronized cardioversion is recommended, even in hemodynamically stable patients.…”

“…23 There are fewer data supporting the use of β-blockers in the acute treatment of SVT; however, they are considered reasonable choices because of their safety profile. 5,23 If all aforementioned pharmacologic therapies fail, synchronized cardioversion is recommended, even in hemodynamically stable patients. 5 In patients presenting in atrial fibrillation who have known Wolff-Parkinson-White or new pre-excitation pattern on ECG, the use of potent AV-nodal blockers (i.e., β-blockers, diltiazem, verapamil and digoxin) should be avoided because these medications may potentiate conduction over the accessory pathway and lead to potentially life-threatening ventricular arrhythmias.…”

New therapeutics and drugs available in Turkey

“…Kalsiyum kanal blokörlerinin yavaş infüz-yon şeklinde uygulanmasıyla görülen hipotansiyon oranının azaltılabildiği de ispatlanmıştır. [17] Etkinlikleri denk olarak ispatlanmış bu iki ajan arasında tercih yaparken her hastanın durumunu ayrı ayrı göz önüne alarak o hasta için en uygun ajan tercih edilmelidir. [16] Flurbiprofen %0.25 oral sprey (Majezik sprey®)…”