“Slow kill” treatment reduces DNA damage in leukocytes of dogs naturally infected with Dirofilaria immitis

Rajković, Milan; Glavinić, Uroš; Bogunović, Danica; Vejnović, Branislav; Davitkov, Darko; Đelić, Ninoslav; Stanimirović, Zoran

doi:10.1016/j.vetpar.2023.110008

Veterinary Parasitology

2023

DOI: 10.1016/j.vetpar.2023.110008

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“Slow kill” treatment reduces DNA damage in leukocytes of dogs naturally infected with Dirofilaria immitis

Milan Rajković,

Uroš Glavinić,

Danica Bogunović

et al.

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2024

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Oxidative Stress in Canine Diseases: A Comprehensive Review

Blanca,

María Luisa,

Guadalupe

et al. 2024

Antioxidants

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Oxidative stress (OS), defined as a disruption in redox balance favoring oxidants, has emerged as a major contributor to numerous diseases in human and veterinary medicine. While several reviews have explored the implication of OS in human pathology, an exhaustive review of the canine species is lacking. This comprehensive review aims to summarize the existing literature on the role of OS in canine diseases, highlighting its potentially detrimental effect on various organs and systems. Some inconsistencies among studies exist, likely due to varying biomarkers and sample types. However, there is substantial evidence supporting the involvement of OS in the development or progression of numerous canine disorders, such as cardiovascular, oncologic, endocrine, gastrointestinal, hematologic, renal, neurologic, infectious, and parasitic diseases, among others. Additionally, this review discusses the efficacy of antioxidant and pro-oxidant therapeutic agents for these conditions. Dietary interventions to counteract OS in dogs have gained significant attention in recent years, although further research on the topic is needed. This review aims to serve as a foundational resource for future investigations in this promising field.

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Oxidative Stress in Canine Diseases: A Comprehensive Review

Blanca,

María Luisa,

Guadalupe

et al. 2024

Antioxidants

View full text Add to dashboard Cite

show abstract

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“Slow kill” treatment reduces DNA damage in leukocytes of dogs naturally infected with Dirofilaria immitis

Cited by 1 publication

References 62 publications

Oxidative Stress in Canine Diseases: A Comprehensive Review

Oxidative Stress in Canine Diseases: A Comprehensive Review

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