Sm³⁺ Potentiometric Membrane Sensor as a Probe for Determination of Some Pharmaceutics

Abstract

The increase use of ion sensors in the fields of environmental, agricultural, and medical analysis is stimulating analytical chemists to develop new sensors for fast, accurate, reproducible, and selective determination of various ions. In this study a new samarium membrane sensor was constructed and for the first time, it was applied as a probe in indirect determination of hyoscine, homatropine, and tramadol drugs in their pharmaceutical formulation. The proposed membrane sensor was constructed based on a membrane containing 2% sodium tetraphenyl borate (NaTPB) as an anionic additive, 63% dibutyl phthalate (DBP) as solvent mediator, 5% ionophore, and 30% poly(vinyl chloride) (PVC). The proposed Sm(III) electrode exhibits a Nernstian response of 19.35 AE 0.2 mV per decade of samarium concentration, and has a lower detection limit of 1.0 Â 10 À7 M. The linear range of the sensors was 1.0 Â 10 À7 -1.0 Â 10 À1 M. It works well in the pH range of 3.0 -8.0.

Experimental and PM6/SPARKLE Semiempirical Study of Interaction between 4‐Methoxyphenylcyanamide and Gadolinium(III) as a Fast Polymeric Membrane Sensor

“…An increase in the potential can be detected at pH < 4.1 because the sensor response to the hydrogen ions. At the higher pH values (pH > 8.3) the observed smooth potential drift is due to the formation of Gd 3 + hydroxyl complex (Gd(OH) 3 ) in the solution.…”

Fabrication A Composite Electrode Based on MWCNT/Zeolite for Potentiometric Determination of Chromium (III)

“…This can prevent an increased in the electrical resistance of the electrode .Then Electrical contact was made by inserting a copper wire in to the opposite end. The working surface of the electrode was polished by using soft abrasive paper.Then, the electrode was conditioned for 24h by being soaked in a 1.0×10 -3 mol L -1 of Cr (NO 3 ) 3 solution [36][37][38][39] .…”

“…The measurement range of an ISE is defined as the upper and lower detection limits, that in the range, response of the electrode obeys of nernst equation [38][39][40] . The response of the electrode with optimal combination was tested in Cr (III) ion concentration range of 1.0,)10 …”

Separation and direct detection of heavy lanthanides using new ion-exchange chromatography: fast Fourier transform continuous cyclic voltammetry system

“…Potentiometric sensors can offer an acceptable sensitivity, selectivity, inexpensive, and convenient method for rare-earth ions analysis in solution. There are many reports about ion selective electrodes (ISEs) for lanthanide ions in last decade [26][27][28][29][30][31][32][33][34][35]. In this study, fast Fourier transform continuous cyclic voltammetry (FFT-CCV) was investigated as a new method for determination of holmium, erbium, thulium, ytterbium, and lutetium.…”