Small Cell Carcinoma of the Hypopharynx

Abstract

Small cell carcinoma is rarely found to originate from the hypopharynx and there exists no treatment guidelines due to the small number of cases. Here, we present a case of a female patient with metastatic small cell carcinoma originating from the posterior hypopharynx with lymph node involvement. Her treatment consisted of chemotherapy with etoposide and cisplatin as well as radiation therapy. Her post-treatment computed tomography (CT) scan indicated resolution of the disease at the primary site and follow-up positron emission tomography (PET)-CT scan at three-month post radiation therapy revealed that the patient is clear of the disease.

Surgical palliation in poorly differentiated neuroendocrine carcinoma of the hypopharynx: Case report

“…Conversely, current literature includes only a limited number of pure hypopharyngeal NECs. 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 Table 1 summarises their main characteristics.…”

“…Conversely, current literature includes only a limited number of pure hypopharyngeal NECs 9–25 . Table 1 summarises their main characteristics.…”

“…7 Literature supports the evidence that the best treatment available for poorly differentiated NECs of the larynx is platinum-based chemotherapy with concomitant radiotherapy, although surgery alone has also been proposed, as well as surgery followed by chemoradiotherapy (CRT). 7,8 The limited number of patients presenting with a NEC of the hypopharynx have seemingly been treated with multimodal therapy, achieving differing outcomes.. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] The work was carried out at Northwick Park Hospital Watford road HA1 3UJ, Harrow, London, UK.…”

“…The limited number of patients presenting with a NEC of the hypopharynx have seemingly been treated with multimodal therapy, achieving differing outcomes. 9–23 …”