Small-cell carcinoma of the lung presenting as a cutaneous metastasis of the lip mimicking a Merkel cell carcinoma

Argila, De; Bureo,; Márquez,; Pimentel, Andy D.

doi:10.1046/j.1365-2230.1999.00445.x

Cited by 17 publications

(13 citation statements)

References 5 publications

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“…Metasta- ses of the scalp lead to the assumption of basal cell carcinoma, epidermal cyst, adnexal tumour or alopecia not speciWed as neoplastica Snow et al 2001). A solitary cutaneous metastasis of a bronchial carcinoma described as painful, dome-shaped on sun-exposed skin was compared with a Merkel cell carcinoma (De Argila et al 1999). DiVerential diagnoses of a lip tumour caused by a pleuromesothelioma were keratoacanthoma and squamous cell carcinoma (Cassarino et al 2003).…”

Section: Diverential Diagnosesmentioning

confidence: 99%

Cutaneous metastases of visceral tumours: a review

Nashan

Müller

Braun‐Falco

et al. 2008

J Cancer Res Clin Oncol

116

136

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Section: Diverential Diagnosesmentioning

confidence: 99%

Cutaneous metastases of visceral tumours: a review

Nashan

Müller

Braun‐Falco

et al. 2008

J Cancer Res Clin Oncol

116

136

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“…24 SCNCs presenting initially in head and neck sites may be metastases from distant sites, which in several cases are the lungs. Metastases from pulmonary and extrapulmonary SCNC have been reported in the hard palate and infra-orbital region, 25 tongue base, 26 tonsils, 27 bilateral parotid gland, 28,29 submandibular gland, 30 nose, 31 lip, 32 and gingiva. 33 There are also 5 cases of laryngeal metastases from pulmonary (3 cases), tracheal (1 case), and prostatic SCNC (Table 1).…”

Section: Incidencementioning

confidence: 99%

Primary and secondary small cell neuroendocrine carcinoma of the larynx: A review

Ferlito

Rinaldo

2008

Head & Neck

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Primary laryngeal small cell neuroendocrine carcinoma (SCNC) is an unusual malignancy accounting for <0.5% of laryngeal carcinomas. To date, approximately 200 cases of primary and 5 of secondary SCNC of the larynx have been reported. This tumor most often presents in the sixth and seventh decades in men who are heavy cigarette smokers. The lesion may be associated with different paraneoplastic syndromes (ectopic adrenocorticotropic hormone syndrome, Schwartz-Bartter syndrome or syndrome of inappropriate secretion of antidiuretic hormone, and Eaton-Lambert myasthenic syndrome) or with ectopic hormone production. The diagnosis is based essentially on the histologic appearance of the tumor, confirmed by immunocytochemical investigations. Concurrent chemoradiotherapy regimens offer potential for long-term survival. This tumor is biologically aggressive, and the extent of the disease is the most significant independent prognostic factor of survival. The survival rate is similar to that with pulmonary SCNC.

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“…In the PubMed database, we found 20 cases with skin metastasis from SCLC (1-12). Among them, precise clinical courses were described in 15 cases (2)(3)(4)(5)(6)(8)(9)(10)(11). Table 1 showed the clinical features of SCLC patients with skin metastasis.…”

Section: Discussionmentioning

confidence: 99%

Skin metastasis from small cell lung cancer

Kurishima¹,

Kagohashi²,

Ohara³

et al. 2014

Tuberk Toraks

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Skin metastasis from small cell lung cancer Patients with skin metastasis always had disseminated metastases in many organs. We herein report an unusual case with skin metas-me tasis from small cell lung cancer (SCLC). The patient was treated with platinum-containing chemotherapy, and the response to o the o therapy was evaluated as partial response. The patient had slowly progressive disease and died of SCLC 16 months after the diagno-ag sis of the diseases. If skin lesions, whether it may be typical or not, are found in SCLC patients, biopsy from the lesion would be ld considered to perform. Although trunk may be the most common sites, it is important to suspect such metastasis occurs in patients ti with SCLC.

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Small-cell carcinoma of the lung presenting as a cutaneous metastasis of the lip mimicking a Merkel cell carcinoma

Cited by 17 publications

References 5 publications

Cutaneous metastases of visceral tumours: a review

Cutaneous metastases of visceral tumours: a review

Primary and secondary small cell neuroendocrine carcinoma of the larynx: A review

Skin metastasis from small cell lung cancer

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