Small-Dose Hyperbaric Versus Plain Bupivacaine During Spinal Anesthesia for Cesarean Section

Abstract

A small dose of hyperbaric bupivacaine 0.5% combined with sufentanil used intrathecally during cesarean section offered a more reliable cephalad spread of the spinal block than the glucose-free combination, which was reflected in a lower incidence of hypotension and nausea.

Spinal anesthesia with sequential administration of plain and hyperbaric bupivacaine provides satisfactory analgesia with hemodynamic stability in cesarean section

“…4,[18][19][20] Vercauteren et al used a combination of sufentanil 3.3 lg with plain or hyperbaric bupivacaine 6.6 mg in 2 mL for spinal anesthesia as part of a combined spinal-epidural procedure in cesarean section. 21 In their study, individual variability was pronounced in the plain group, and significantly more patients in the plain group had blocks that were either too high or too low. Although hypotension was more pronounced in the plain group (21% vs. 6% in the hyperbaric group), their overall incidence was 13%, lower than that of other studies using higher doses, and similar to our PHB group (13.9%).…”

Low-dose ropivacaine-sufentanil spinal anaesthesia for caesarean delivery: a randomised trial

“…Several previous studies 2, 16,17 have demonstrated that a low dose of spinal local anaesthetic is associated with a low incidence of hypotension. However, these studies were flawed because of the lack of a control group.…”

Anästhesiologisches Management der Sectio caesarea

“…Mit nur 60,8% ist die Rate der Opioidbeimischung in Deutschland verbesserungswürdig. Bezüglich der Barizität des Lokalanästheti-kums gibt es Daten, die eine bessere Zuverlässigkeit und Steuerung der Blockadeausdehnung der hyperbaren Lösung insbesondere im Niedrigdosisbereich bei SC belegen [13,25].…”