Small Dysplastic Congenital Melanocytic Nevi in Childhood as Possible Melanoma Imitators

Abstract

Small pigmented lesions in children can represent a significant diagnostic challenge. If the diagnostic features and therapeutic approach are relatively well established in large and giant nevi, there is still much controversy regarding small and intermediate-sized congenital pigmented lesions that can lead to significant diagnostic challenges, both clinically and dermoscopically, and consequently to difficulty in defining the optimal approach in such cases. Although dermoscopy can be useful in the diagnosis of pigmented lesions, the diversity of clinical and dermoscopic features of pigmented nevi in children usually hinder the differentiation between them and melanoma. Histological findings after resection often show surprising results that do not correspond either to the clinical nor the dermoscopic features. With the present case, we want to emphasise the variable natural behaviour of melanocytic lesions in children, which sometimes leads to unnecessary surgical excisions, which should be avoided in pediatric patients.

A Sheep in Wolf’s Clothing: Lobular Pyogenic Granuloma Masquerading Nodular Amelanotic Melanoma

“…The pattern composed of ‘reddish homogeneous area’, ‘white rail lines’ and ‘vascular structures’ showed the highest sensitivity (22.1%) and specificity (100%) for pyogenic granuloma [7]. Other lesions that might masquerade melanoma include small atypical congenital melanocytic nevi [8] and hypercellular encapsulated neuroma [9].…”