Small field dose measurements using plastic scintillation detector in heterogeneous media

Xue, Jiangyu; McKay, Jesse D.; Grimm, Jimm; Cheng, Chee Wai; Berg, Ronald; Grimm, Shu Ya Lisa; Xu, Qiang; Subedi, Gopal; Das, Indra J.

doi:10.1002/mp.12272

Cited by 15 publications

(6 citation statements)

References 25 publications

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“…A third example of discovery from the opposite direction of the original goal is the present study, which began as a quest to achieve submillimeter end-to-end accuracy on any stereotactic linac ( 75 ) but differences in outcomes among the various systems were observed. Soon, the tests validated that continuous live respiratory motion management indeed can achieve submillimeter end-to-end targeting accuracy and excellent dosimetric accuracy in a wide variety of situations ( 44 , 76 , 77 ), and the resulting clinical outcomes comparatively appear exceptionally good, as summarized in this study. This was also seen in the series of publications in the NTCP for SBRT issue of Seminars in Radiation Oncology ( 78 ).…”

Section: Discussionsupporting

confidence: 60%

“…Systematic, standardized, and uniform data collection of treatment parameters and complications are lacking. Technically, physics measurements have shown that the even with respiratory motion management and in lung material, ray tracing algorithm can be off by up to 120%, although improved measurements by some of the same authors later matched the Monte Carlo algorithm within 3% ( 77 , 79 ). Similarly, when motion management techniques were used without multiple fiducials and synchrony tracking, the risk of duodenal complications was found to be five times higher ( 28 ).…”

Section: Discussionmentioning

confidence: 99%

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Potential Clinical Significance of Overall Targeting Accuracy and Motion Management in the Treatment of Tumors That Move With Respiration: Lessons Learnt From a Quarter Century of Stereotactic Body Radiotherapy From Dose Response Models

et al. 2021

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ObjectiveTo determine the long-term normal tissue complication probability with stereotactic body radiation therapy (SBRT) treatments for targets that move with respiration and its relation with the type of respiratory motion management (tracking vs. compression or gating).MethodsA PubMed search was performed for identifying literature regarding dose, volume, fractionation, and toxicity (grade 3 or higher) for SBRT treatments for tumors which move with respiration. From the identified papers logistic or probit dose-response models were fitted to the data using the maximum-likelihood technique and confidence intervals were based on the profile-likelihood method in the dose-volume histogram (DVH) Evaluator.ResultsPooled logistic and probit models for grade 3 or higher toxicity for aorta, chest wall, duodenum, and small bowel suggest a significant difference when live motion tracking was used for targeting tumors with move with respiration which was on the average 10 times lower, in the high dose range.ConclusionLive respiratory motion management appears to have a better toxicity outcome when treating targets which move with respiration with very steep peripheral dose gradients. This analysis is however limited by sparsity of rigorous data due to poor reporting in the literature.

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Section: Discussionsupporting

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Potential Clinical Significance of Overall Targeting Accuracy and Motion Management in the Treatment of Tumors That Move With Respiration: Lessons Learnt From a Quarter Century of Stereotactic Body Radiotherapy From Dose Response Models

et al. 2021

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“…In addition, these scintillators can perform real-time measurements with a high spatial resolution. This makes plastic scintillation detectors (PSD) attractive for small fields or highly modulated beam measurements (Xue et al 2017).…”

Section: Introductionmentioning

confidence: 99%

On the use of polychromatic cameras for high spatial resolution spectral dose measurements

2022

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Objective: Despite the demonstrated benefits of hyperspectral formalism for stem effect corrections in the context of fiber dose measurements, this approach has not been yet translated into volumetric measurements where cameras are typically used for their distinguishing spatial resolution. This work investigates demosaicing algorithms for polychromatic cameras based spectral imaging. Approach: The scintillation and Cherenkov signals produced in a radioluminescent phantom are imaged by a polychromatic camera and isolated using the spectral formalism. To do so, five demosaicing algorithms are investigated from calibration to measurements: a clustering method and four interpolation algorithms. The resulting accuracy of scintillation and Cherenkov images is evaluated with measurements of the differences (mean ± standard deviation) between the obtained and expected signals from profiles drawn across a scintillation spot. Signal-to-noise ratio and signal-to-background ratio are further measured and compared in the resulting scintillation images. Finally, the resulting differences on the scintillation signal from a 0.2x0.2 cm^2 region-of-interest (ROI) were reported. Main results: Clustering, OpenCV, bilinear, Malvar and Menon demosaicing algorithms respectively yielded differences of 3±5%, 1±3%, 1±3%, 1±2% and 2±4% in the resulting scintillation images. For the Cherenkov images, all algorithms provided differences below 1%. All methods enabled measurements over the detectability (SBR>2) and sensitivity (SNR>5) thresholds with the bilinear algorithm providing the best SNR value. Clustering, OpenCV, bilinear, Malvar and Menon demosaicing algorithms respectively provided differences on the ROI analysis of 7±5%, 3±2%, 3±2%, 4±2%, 7±3%. Significance Radioluminescent signals can accurately be isolated using a single polychromatic camera. Moreover, demosaicing using a bilinear kernel provided the best results and enabled Cherenkov signal subtraction while preserving the full spatial resolution of the camera.

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Section: Introductionmentioning

confidence: 99%

Technical note: On the use of polychromatic cameras for high spatial resolution spectral dose measurements

Cloutier¹,

Beaulieu²,

Archambault³

2021

Preprint

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Despite the demonstrated benefits of hyperspectral formalism for stem effect corrections in the context of fiber dose measurements, this approach has not been yet translated into volumetric measurements where cameras are typically used for their distinguishing spatial resolution. This work investigates demosaicing algorithms for polychromatic cameras based spectral imaging. The scintillation and Cherenkov signals produced in a radioluminescent phantom are imaged by a polychromatic camera and isolated using the spectral formalism. To do so, five demosaicing algorithms are investigated from calibration to measurements: a clustering method and four interpolation algorithms. The resulting accuracy of scintillation and Cherenkov images is evaluated with measurements of the differences (mean ± standard deviation) between the obtained and expected signals from profiles drawn across a scintillation spot. Signal-to-noise ratio and signal-to-background ratio are further measured and compared in the resulting scintillation images. Clustering, OpenCV, bilinear, Malvar and Menon demosaicing algorithms respectively yielded differences of 3±6%, 0.1±0.5%, 0.5 ± 0.5%, 1 ± 3% and 1 ± 4% in the resulting scintillation images. For the Cherenkov images, all algorithms provided differences below 1%. All methods enabled measurements over the detectability (SBR > 2) and sensitivity (SNR > 5) thresholds with the bilinear algorithm providing the best SNR value. Hence, radioluminescent signals can accurately be isolated using a single polychromatic camera. Moreover, demosaicing using a bilinear kernel provided the best results and enabled stem effect subtraction while preserving the full spatial resolution of the camera.

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Small field dose measurements using plastic scintillation detector in heterogeneous media

Cited by 15 publications

References 25 publications

Potential Clinical Significance of Overall Targeting Accuracy and Motion Management in the Treatment of Tumors That Move With Respiration: Lessons Learnt From a Quarter Century of Stereotactic Body Radiotherapy From Dose Response Models

Potential Clinical Significance of Overall Targeting Accuracy and Motion Management in the Treatment of Tumors That Move With Respiration: Lessons Learnt From a Quarter Century of Stereotactic Body Radiotherapy From Dose Response Models

On the use of polychromatic cameras for high spatial resolution spectral dose measurements

Technical note: On the use of polychromatic cameras for high spatial resolution spectral dose measurements

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