Small field-of-view cardiac SPECT can be implemented on hybrid SPECT/CT platforms where data acquisition and reconstruction are guided by CT

Sabondjian, Eric; Stodilka, Robert Z.; Belhocine, Tarik; King, M.; Wisenberg, Gerald; Prato, Frank S.

doi:10.1097/mnm.0b013e32832eabec

Cited by 3 publications

(7 citation statements)

References 23 publications

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“…As previously described by Xiao et al small field of view SPECT may exclude the liver from the field of view and thus interfere with scatter correction. 2,3 In our patient, the liver was not excluded and, however, truncation of the distal one-third of the heart was observed. Although the truncation artifact in our case was eventually recognized by the interpreting physician after the scan was completed and the patient had already left the facility, it had not been recognized by the imaging technologist.…”

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confidence: 56%

The truncation artifact

Wosnitzer

Gadiraju

DePuey

2011

Journal of Nuclear Cardiology

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Case report. A 53-year-old male was referred for a single day gated rest/stress Tc-99m sestamibi myocardial perfusion imaging (MPI) study for the evaluation of exertional dyspnea. His medical history included hypertension and hypercholesterolemia. The patient's height, weight, and chest circumference were 5 0 11 00 , 357 pounds, and 52 in., respectively. A standard single low-dose rest (10.3 mCi)/high-dose stress (31.0 mCi) Tc-99m sestamibi protocol was used. Due to the patient's inability to exercise, a standard dipyridamole pharmacologic stress with 59.6 mg of dipyridamole was performed. The patient experienced no chest pain and there were no ST segment changes during dipyridamole infusion. All images were acquired on a GE Millenium VG with a dual 90°detector system using a 180°circular orbit and a low energy, high-resolution collimator. Images were processed with ordered subset expectation maximization (OSEM) using Myovation software on a GE Xeleris computer.Review of the rotating planar projection images demonstrated truncation of the apex and distal one-third of the left ventricle in both the stress and the rest acquisitions ( Figure 1). Reconstructed tomographic images also showed considerable artifact involving the distal third of the left ventricle rendering this study uninterpretable (Figure 2).Since the patient had already left the testing facility, immediate repeat post-stress imaging was not possible and an entire repeat study was scheduled for 2 days later. The repeat study used the same protocol with rest/ stress doses of 10.4/31.2 mCi of Tc-99m sestamibi and 60.0 mg of dipyridamole, but with a circular camera orbit having a larger radius of rotation to accommodate the patient's girth. Again, the patient experienced no chest pain, and there were no ST segment changes during dipyridamole infusion. In the repeat stress and rest rotating planar projection images, the apex and the distal one-third of the left ventricle were no longer truncated (Figure 3). The tomographic images also demonstrated no truncation artifact. There was homogeneous tracer distribution throughout the entire left ventricular myocardium, indicating no scan evidence of either scar or dipyridamole-induced ischemia (Figure 4).Discussion. Recognizing and understanding imaging artifacts is necessary for physicians to properly acquire and accurately interpret myocardial perfusion scans. The truncation artifact occurs when the patient is large relative to the field of view of the camera, causing part of the body to be outside of the camera's view. 1

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confidence: 56%

The truncation artifact

Wosnitzer

Gadiraju

DePuey

2011

Journal of Nuclear Cardiology

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“…18 Third, for iterative methods, the system matrix (SM) must be large enough to contain the entire object even if only a ROI is to be reconstructed. In addition, with the fulfillment of these conditions, studies also demonstrated that the use of body contour as a support in reconstruction could effectively reduce bias and artifacts caused by projection truncation in both transmission 9,19 and emission 12,15,20 applications. A more recent study suggested that when projections are truncated, sufficient angular sampling (e.g., >60 views over 180 • rotation) is required to have a quantitative and artifact free reconstruction, otherwise the solution is not unique even when a subregion value is known as a priori knowledge.…”

Section: Introductionmentioning

confidence: 97%

“…13,14 Sabodjian et al simulated a small FOV system (16 × 16 cm) by artificially truncating the data from patient studies acquired on a two-head GE Infinia-Hawkeye system, and showed that the reconstructions of the truncated projections yielded over 100% overestimation in the myocardium, and on average a 17% reduction in defect size. 15 Xiao et al, on the other hand, investigated the impact of truncations that occurred only in the axial direction. Their results suggested that the impact of truncations on single isotope SPECT was insignificant and should not affect clinical diagnosis.…”

Section: Introductionmentioning

confidence: 99%

The impact of system matrix dimension on small FOV SPECT reconstruction with truncated projections

Chan

Dey

Grobshtein³

et al. 2015

Med. Phys.

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“…According to the principle of tomography, images cannot be reconstructed accurately using truncated projection data [3]. Therefore, an artifact, known as a truncation artifact occurs in reconstructed tomographic images [4][5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

“…Most studies of truncation artifacts in myocardial perfusion SPECT have reported on the effects of the attenuation maps generated from a truncated transmission data on the reconstructed image [4][5][6][7]. On the other hand, a few studies have investigated whether the truncation artifact affects the myocardial image without attenuation correction if the myocardial image is not truncated outside the FOV at any projection view, but the radioactivity of body tissue is truncated at some views [8][9][10]. Image reconstructed from truncated projection data display various artifacts and distortions.…”

Section: Introductionmentioning

confidence: 99%

Prerequisite for projection data and reconstruction not to cause truncation artifacts in myocardial perfusion single-photon emission computed tomography: Phantom study

Tsuboi¹,

Onoguchi²,

Sugimoto³

et al. 2020

SJC

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Myocardial perfusion single-photon emission computed tomography (SPECT) studies are used widely in the evaluation and diagnosis of coronary artery disease. Although one method to improve the spatial resolution is zooming acquisition, truncation artifact occurs in reconstructed tomographic images. To date, it is unclear how much truncation (area and radioactivity) of projection data would affect myocardial image. The aim of this study is to investigate the combination of truncated projection data conditions and image reconstruction methods that do not require re-examination. We used a cylindrical and anthropomorphic torso phantom with 99mTc solution, and shifted the projection data to simulate truncated liver tissue. SPECT images were acquired using a dual-detector gamma camera and reconstructed using filtered back projection (FBP) and ordered subset expectation maximization (OSEM) to create transverse images. We compared truncation data and reference data (none truncated projection data) for count profile curve, uniformity, myocardial counts, and % uptake. Our findings indicate that prerequisite for truncation data and image reconstruction method would not affect the myocardial image, when the area of truncation was < 17.5% and the count of the truncation portion was lower than that in the myocardium using FBP.

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Small field-of-view cardiac SPECT can be implemented on hybrid SPECT/CT platforms where data acquisition and reconstruction are guided by CT

Abstract: Projection truncation due to small FOV cameras in cardiac SPECT/CT can lead to significant errors. TMOSEM guided by nontruncated CT reconstruction shows promise in reducing these errors.

Cited by 3 publications

References 23 publications

The truncation artifact

The truncation artifact

The impact of system matrix dimension on small FOV SPECT reconstruction with truncated projections

Prerequisite for projection data and reconstruction not to cause truncation artifacts in myocardial perfusion single-photon emission computed tomography: Phantom study

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