2022
DOI: 10.1101/2022.05.27.493742
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Small Noncoding Rna Contents of Rat Epididymal Extracellular Vesicles Including a Putative Novel Small Rna

Abstract: Extracellular vesicles (EVs) released from the epididymal epithelium (epididymosomes) impart functional competence on sperm as they transit the epididymis by merging with sperm and releasing a complex repertoire of molecules. The cargo of epididymosomes includes small noncoding RNAs (sncRNAs) that are modified by external factors such as stress, nutrition, and drug use. If incorporated into sperm, the EV sncRNA cargo can affect offspring and lead to heritable phenotypes. In the current study we characterized t… Show more

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