2019
DOI: 10.1016/j.biopha.2019.108826
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Small RNA-sequencing identified the potential roles of neuron differentiation and MAPK signaling pathway in dilated cardiomyopathy

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Cited by 13 publications
(23 citation statements)
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“…Huang et al (2019) concluded that 23 differential dysregulated miRNAs were identi ed in plasma of DCM patients, and those miRNAs associated with MAPK signaling pathway. The same authors pointed that FGFR4, FGFR1 and ACNA1 were hub target mRNAs in MAPK signaling pathway in the studies DCM patients [33].…”
Section: Discussionmentioning
confidence: 90%
“…Huang et al (2019) concluded that 23 differential dysregulated miRNAs were identi ed in plasma of DCM patients, and those miRNAs associated with MAPK signaling pathway. The same authors pointed that FGFR4, FGFR1 and ACNA1 were hub target mRNAs in MAPK signaling pathway in the studies DCM patients [33].…”
Section: Discussionmentioning
confidence: 90%
“…Based on the 2 miRNAs with significant expression differences, all target genes in miRanda, RNAhybrid, and miRDB database were predicted [ 31 , 32 ].…”
Section: Resultsmentioning
confidence: 99%
“…Selenium deficiency may also increase the infection of enterovirus and other pathogens, through the above-mentioned mechanism, leading to the occurrence and progress of KSD, and finally causing heart failure (3,(6)(7)(8). In a previous study by this research team, miRNA sequencing was also conducted in patients with dilated cardiomyopathy, and bioinformatic analysis revealed that a neuronal differentiation process and a mitogenactivated protein kinase (MAPK) signaling pathway were involved in the occurrence and development of dilated cardiomyopathy (14). Therefore, there are some differences in miRNA between KSD and dilated cardiomyopathy.…”
Section: Discussionmentioning
confidence: 99%