2024
DOI: 10.1002/hbm.26634
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Small vessel disease and cognitive reserve oppositely modulate global network redundancy and cognitive function: A study in middle‐to‐old aged community participants

Lei Cui,
Hui Hong,
Shuyue Wang
et al.

Abstract: Cerebral small vessel disease (SVD) can disrupt the global brain network and lead to cognitive impairment. Conversely, cognitive reserve (CR) can improve one's cognitive ability to handle damaging effects like SVD, partly by optimizing the brain network's organization. Understanding how SVD and CR collectively influence brain networks could be instrumental in preventing cognitive impairment. Recently, brain redundancy has emerged as a critical network protective metric, providing a nuanced perspective of chang… Show more

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