Smaller Foveal Avascular Zone in Deep Capillary Plexus Is Associated with Better Visual Acuity in Patients after Macula-off Retinal Detachment Surgery

Abstract

Smaller foveal avascular zone in deep capillary plexus is associated with better visual acuity in patients after macula-off retinal detachment surgery.

Association between retinal vessel density and postoperative time after primary repair of rhegmatogenous retinal detachment

“…Ng et al associated the change in the FAZ and VD with final BCVA in eyes after macula-off RRD surgery, and investigated the evolution of FAZ and VD during 12 months of follow-up. At 12 months postoperatively, FAZ difference of the DCP and BCVA difference were correlated, and there was no evidence that FAZ and VD changed during followup [19].…”

Untitled

“…Retinal microvasculature of the two capillary plexuses (SCP and DCP) and choriocapillary network are evaluated in detail, while ICP is not always included in most studies due to projection artifact [9][10][11]. Notably, the currently available evidence concerning potential macular alterations as seen on OCT-A after RRD repair has stirred controversy as the results of the studies have not been unequivocally confirmed [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31].…”

“…Obviously, gas is a widely utilized tamponading agent and its use accounts for a large fraction of cases [32][33][34][35][36][37][38][39]. Indeed, most studies comprehensively examine OCT-A characteristics of RRD eyes after PPV with gas tamponade [13][14][15][16][17][18][19][20][21][22][23][29][30][31], while there is limited evidence of those treated by PPV with SO or by scleral buckle [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]. The primary anatomical success rates for RRD repair by PPV have been found to range from 64% to 96%.…”

“…Since angiogenesis has been associated with improved functional outcomes, we could expect recovery of VA. Indeed, therapeutic stimulation of angiogenesis in these cases could be beneficial to photoreceptor regeneration and in turn improved functional outcomes [30,68].…”

“…Potential selection bias could be confounding factor of their results. Owing to the inter-individual variability of OCT-A parameters, it would be of additional value for all studies to interpret the OCT-A parameters of the RRD eye in reference to the fellow eye to avoid physiological differences among healthy subjects that may produce inconsistent results [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31].…”