“Smart” carboxymethylchitosan hydrogels crosslinked with poly(N-isopropylacrylamide) and poly(acrylic acid) for controlled drug release

Chitosan–Quercetin Bioconjugate as Multi‐Functional Component of Antioxidants and Dual‐Responsive Hydrogel Networks

“…Due to its chemical functionalities (ionizable NH 2 groups), CHIT confers pH responsivity when inserted into hydrogel networks . On the other hand, the simultaneous employment of functional monomers (e.g., N ‐isopropylacrylamide (NIPAAm)) was proved to be a valuable strategy to introduce thermoresponsivity to the whole system, with the obtainment of dual‐sensitive materials …”

Design of robust and photoluminescence‐responsive materials based on poly(methacrylic acid‐co‐m‐phenylenediamine) with graphene oxide composite hydrogels and its adsorption

“…The traditional sense of a hydrogel is a kind of polymer with three‐dimensional networks, which swells in water but is insoluble . Smart hydrogels, a class of stimulus‐responsive (SR) polymers, have been broadly studied in recent years because of their promising potential in manufacturing intelligent controllable materials, which can display rapid and significant responses to environmental stimuli, such as temperature, ion strength, pH, light, salt, electricity, magnetism, and chemical substances . In the biomedical field, smart hydrogels have lots of practical applications, such as in temperature‐ and pH‐responsive dendrimer systems used to encapsulate and release drugs .…”

“…Smart hydrogels, a class of stimulus‐responsive (SR) polymers, have been broadly studied in recent years because of their promising potential in manufacturing intelligent controllable materials, which can display rapid and significant responses to environmental stimuli, such as temperature, ion strength, pH, light, salt, electricity, magnetism, and chemical substances . In the biomedical field, smart hydrogels have lots of practical applications, such as in temperature‐ and pH‐responsive dendrimer systems used to encapsulate and release drugs . Smart hydrogels possess other potential practical applications, like in sensors, molecular imprinting, protein recognition, enzyme immobilization, and separation of biological molecules or cells …”

Preparação de micropartículas de quitosana incorporadas de nanogéis de poli-(N-vinilcaprolactama-<i>co</i>-ácido itacônico-<i>co</i>-dimetacrilato de etilenoglicol) via secagem por pulverização para liberação controlada de cetoprofeno

“…Assim, esses microgéis e nanogéis podem ser incorporados por interações físicas ou enxertados em outras matrizes poliméricas biodegradáveis, como a quitosana, as quais podem exercer um papel de proteção contra a aglomeração de partículas. Além disso podem aumentar a adesão do sistema de liberação sobre a mucosa do tecido alvo (mucoadesão) ou até mesmo podem ser utilizadas para modificar as propriedades de outra matriz polimérica (formação de compósitos), como o pH ideal para liberação ou para melhorar o controle de liberação do fármaco (WILKE et al, 2015;CONTRI et al, 2014;JANKAEW et al, 2015;HUANG et al, 2014).…”

“…Quitosana Catiônico NOSHAD et al, 2015MAESTRELLI et al, 2015 Alginato Aniônico MAESTRELLI et al, 2015 Quitosana/poli(acrilamida-co-ácido itacônico) Catiônico/aniônico BOCOURT et al, 2014 Carboximetilcelulose-poli(ácido acrílico) Aniônico GAO et al, 2014 Carboximetilquitosana-g-poli(Nisopropilacrilamida)-g-poli(ácido acrílico) Anfótero/aniônico JANKAEW et al, 2015 Quitosana-sílica Catiônico NETO et al, 2014 Poli(N-vinilcaprolactama-co-ácido itacônico) Aniônico WILKE et al, 2015 Poli(N-vinilcaprolactama-co-ácido metacrílico) Aniônico MUNDARGI; RANGASWAMY; AMINABHAVI , 2011…”