Smart electrochemical immunosensor for detection of aspartame in dietary products supported by in silico methods

Hloma, Phathisanani; Uwaya, Gloria Ebube; Bisetty, Krishna

doi:10.1016/j.biosx.2022.100203

Cited by 3 publications

(2 citation statements)

References 31 publications

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“…Detection Ab labeled single-walled carbon nanohorns (SWCNHs)/thionine(thi)/AuNPs has been realized, working as electroactive tracers for the detection of carcinoembryonic antigen, [168] or polyvinylpyrrolidone-capped AgNPs/MWCNTs were conjugated with TIR2 Abs to determine aspartame in food samples. [169] The physical bioconjugation in electrochemical immunosensor fabrication can be achieved both in solution or following a layer-by-layer procedure. As examples, AuNPs-Ab or AgNPs-Ab bioconjugates have been prepared in solution, realizing Ab-tagged bio probes for assemblingandwich-type electrochemical immunosensors.…”

Section: Physical Adsorptionmentioning

confidence: 99%

“…Therefore, a combination of different NMs in producing nanocomposites represents an optimal solution for obtaining synergistic effects in Ab physical adsorption and immunosensing performance, mitigating the risk of extreme denaturation phenomena. Detection Ab labeled single‐walled carbon nanohorns (SWCNHs)/thionine(thi)/AuNPs has been realized, working as electroactive tracers for the detection of carcinoembryonic antigen, [168] or polyvinylpyrrolidone‐capped AgNPs/MWCNTs were conjugated with TIR2 Abs to determine aspartame in food samples [169] . The physical bioconjugation in electrochemical immunosensor fabrication can be achieved both in solution or following a layer‐by‐layer procedure.…”

Section: Antibody Immobilization Strategies On Npsmentioning

confidence: 99%

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Nanoparticles in Electrochemical Immunosensors – A Concept and Perspective

Polli,

Simonetti,

Surace

et al. 2023

ChemElectroChem

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Nanoparticle‐based electrochemical immunosensors are fascinating and promising screening systems that rely on the affinity binding between antibodies and antigens, allowing the specific detection of diverse types of targets (e. g., proteins, hormones, antibodies). The employment of nanoparticles in the realization of such devices dramatically improves the selectivity, sensitivity, and the transducer surface area for effectively immobilizing the bioreceptor or target molecules. During the last years, the nanoparticles design and fabrication was mainly focused on taking advantage from synergistic effects due to the coupling of different materials. In this review, we summarize the very recent advancements in this regard, with specific emphasis to nanoparticle syntheses procedures, antibody oriented immobilization strategies and transduction techniques. Moreover, the last trends and applications have been extensively discussed along with the remaining challenges and future perspectives.

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Section: Physical Adsorptionmentioning

confidence: 99%

Section: Antibody Immobilization Strategies On Npsmentioning

confidence: 99%

Nanoparticles in Electrochemical Immunosensors – A Concept and Perspective

Polli,

Simonetti,

Surace

et al. 2023

ChemElectroChem

View full text Add to dashboard Cite

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A novel electrochemical sensor for the detection of zearalenone in food matrices using PEGylated Fe3O4 nanoparticles supported by in-silico and multidetector AF4

Naidoo

Uwaya

Meier

et al. 2023

Journal of Electroanalytical Chemistry

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Impactos Dos Adoçantes Sintéticos Na Saúde Humana E No Meio Ambiente: Uma Revisão Sistemática

Rita Juliana Da Silva Moura,

Roberto,

Oliveira

et al. 2024

RMNM

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Os adoçantes sintéticos têm sido amplamente utilizados como substitutos do açúcar, tanto por pessoas que buscam reduzir o consumo de calorias quanto por pessoas com diabetes, no entanto, à medida que o uso desses adoçantes aumenta na população, a questão da segurança dos adoçantes sintéticos permanece em constante debate, essa questão está sujeita a pesquisas e discussões contínuas, especialmente em relação aos possíveis efeitos negativos no organismo humano e no meio ambiente, esta revisão tem como objetivo avaliar o impacto destes adoçantes no corpo humano, bem como os seus efeitos ambientais, onde baseou-se em uma pesquisa bibliográfica, trazendo como embasamento uma pesquisa investigativa e avaliativa, foram feitas seleção dos estudos pelo resumo de acordo com os critérios de inclusão e exclusão utilizando estratégias de buscas e resultado primário da busca, no qual se adquiriu resultados valiosos para a pesquisa, as descobertas ressaltam a possibilidade de efeitos adversos a longo prazo, estudos mostram vias de degradação da Sacarina e do Aspartame, no entanto tanto o Aspartame e o Acessulfame-k podem ser considerados preocupantes em termos de seus potenciais efeitos adversos à saúde, já a Sucralose, por outro lado, tem mostrado impactos negativos no meio ambiente, mas é importante notar que a avaliação do adoçante menos recomendado depende da perspectiva e das preocupações específicas. Palavras-chave: Adoçantes sintéticos., Edulcorantes., Saúde.

show abstract

Smart electrochemical immunosensor for detection of aspartame in dietary products supported by in silico methods

Cited by 3 publications

References 31 publications

Nanoparticles in Electrochemical Immunosensors – A Concept and Perspective

Nanoparticles in Electrochemical Immunosensors – A Concept and Perspective

A novel electrochemical sensor for the detection of zearalenone in food matrices using PEGylated Fe3O4 nanoparticles supported by in-silico and multidetector AF4

Impactos Dos Adoçantes Sintéticos Na Saúde Humana E No Meio Ambiente: Uma Revisão Sistemática

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